Started taking Mirtazapine 15mg beginning of week, initially in combination with Sertraline.

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Given Mirtazapine to help serious long-standing insomnia, with plan to drop Sertraline in 2 weeks.  First night 6 hours sleep, second 4 hours, third only 2 hours, even with Zopiclone.  Today I feel more suicidal than I ever have done. Total lack of any feeling of self-worth.  Has anybody else out there had this reaction?  My GP is on holiday and I feel unable to speak to anyone else.

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    Hey hun, it took about a month of taking mirtazapine to start fully working, although some side effects will make you feel worth so maybe stop taking it although i'm not a professional...dont suffer in silence if you feel so bad go to A&E or maybe a walk in centre...i've been there trust me and its awful...i'm coming off mirtazapine and its the worst.  good luck
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    Hi Susan.  I also suffer from chronic insomnia. Having been on Zopiclone for many years, my gp decided it was time to come of them and when i mentioned i was anxious about that she prescribed Mirtazapine.  Of course, i hardly slept at all also i didnt like the side effects, grogginess next day and restless legs at night.  When i went back to report these symptoms and asked her if there was something else i could take she refused point blank. I feel so let down so have now resorted to buying of the internet.  Without out sleep it is easy to feel suicidal, felt dreadful myself, zombie like and just going through the motions of life, not living it. Can you go see another gp, you really ought to.  I am ok with the Zops on their own in conjunctions with Melatonin tablets.  Please see a gp asap.
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