Starting on venlafaxine.
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Been on 20mg cit and 37.5 mg ven for 10 days. Have been conistantly low. Just reduced cit to 10mg, and increased ven to 75mg. Have to do this for 2 weeks, then can increase ven up to 150mg depending on what I end up needing. Has anyone done this tapered switch, and can I expect some improvement in mood over next few weeks, or will it come once I go completely onto ven at a higher dose. Door mood, ie depression, I tend to need high dosages, but anxiety got too bad. These were on ssris, now giving ven a snri a go. Just looking for experience of this please? Thanks
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jennifer21990 nigel45109
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nigel45109 jennifer21990
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So far, you have been taking a ssri class of drug, that works on seratonin only. With effexor, it's similar, but works on seratonin and norepinedrene, so it's not a single action like a Ssri, but a dual action instead. Snri tends to work better where ssris haven't.
nigel45109
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Effexor is a good choice if ssris haven't worked well. It's more effective at treating stubborn depression.
jennifer21990 nigel45109
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nigel45109 jennifer21990
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Seroxat stopped working for me in December. 13 weeks on citalopram seem to make me worse. This basically meant ssris were not treating my depression well enough, causing too much anxiety, hence starting effexor, which is tried after ssris don't work. Effexor is more for depression than anxiety, although it still does both. Unfortunately it can take a few tries until you find the right one. Citalopram caused me so much anxiety am taking diazepam now as well. Effexor works on 2 chemicals in the brain, rather than 1 with ssris you tried before. Old style anti depressants also worked on both. Old style ones are just as effective as new ssri and snris, but have too many side effects. Ssris are tried first, as for most people they work for. Usually their depression is not quite so bad, hence they work. Effexor I think is more effective at treating depression, so after a while on it, you shouldn't get the anxiety. Talk to your doctor about taking diazepam while switching. It's helping me a lot with the anxiety, though have to use it sparingly, as otherwise it sedated you too much.
jennifer21990 nigel45109
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nigel45109 jennifer21990
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Thanks for asking. Really low to be honest, although last couple of hours eased off a little. Bit more anxious, so probably a sign they're working. Think you get worse before better. Although really Low, didn't get a lot done today, which I didn't want to do. I've been on 75mg for 6 days now. 2 weeks on 35.7mg before. To be honest, don't think 35.7 does much apart from get you used to it. 150 mg is the usual dose that leads to recovery. Waiting is the hardest part. Thinking how can I possibly think positive and recover again, when everything feels so bad now. I know logically that I should get better eventually, but doesn't feel like it. That's the hard part of sticking with it. Ven gets a lot of bad coverage on here. But elsewhere very positive reviews. Only bad coming off it, which you have to do carefully, or stay with them if it makes you feel good. There aren't too many choices if you want to get better.
nigel45109
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My choices were ven or mirtazapine, as next line to try after ssris didn't work for me. Didn't fancy weight get and drowsiness associated with mirtazapine. I chose on what would give me best outcome, which is ven, if it works. Will be a bad choice if if doesn't.
sarah24378 nigel45109
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