still having migraines

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I have had migraines since i was 12 (I'm almost 28 now) and over the years they have become increasingly frequent. It got to the stage where i was having 4-5 severe ones a week. I'm a medical student so this was REALLY getting in the way of life and i just used to wander round in a painkiller induced daze or be forced to collapse in bed.

A few weeks ago I came to the end of my tether. despite being on beta blockers and antidepressants and armed with seriously strong painkillers and all sorts of things like sumatriptam i was still completely incapacitated with a 4 day migraine. So i took the plunge and tried the pizotifen 1.5mg given by by GP.

Three days went by with no mirgaine... then a small migraine then another 4 day whopper probably more severe than before which knocked me out cold for the whole weekend and beyond. I've been on the pizotifen for 2 weeks now and low and behold today - another migraine.


So what i want to know is.... what is most peeople's experience of the drug? if its going to work for you will it work straight away or do you have to stick with it for months before the 'effect' kicks in... and what can i do in the meantime?! I really don't know how long to stick with it because on top of the pain i'm also ballooning in weight!


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  • Posted


    Have just found this site and your post from last year and was wondering how you are getting on ?

    My boyfriend only started to take these 4 days ago and still has migraines - but if he knew of a success story - that would definately help him.


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  • Posted

    hi, have been on these pills now for 5 weeks - still getting migraines but as I take one pill before bed every night I seem to be getting a good night sleep but headaches are still happening - when will I ever have a normal life again! sad
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  • Posted

    I used to get migraines especially round that time of the month but then I was put on propanolol x3 day and that seemed to stop them
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  • Posted

    Hi all, I have been on these for about a year an a half as I used to get bad migraines that knocked me for six for a good seven + hours, some upto 2 days. Mine primarily came on from early mornings during the week and late nights, late mornings at weekends (plus the stress of running a nightclub).

    Firstly, you need to stay on them for a good month or two before you get the continuous benefit from them, if I even miss one day I find I have a worse headache in two weeks time. But I have found that my headaches have become a lot less frequent and only annoying (where as before if I even spoke I was physically sick). I have also been perscribed 'Zomig' tablets for when I feel a headache coming on and these are miracle tablets, my headache clears in 5 mins (seriously, with no side effects!) But, and there is a big but, they are mega expensive to perscribe and you only get six in a pack. So on going to my doctor about six months ago to get more he suggested I try 900mg of Asprin and only use 'Zomig' in a real bad case. So I did and I have found this to work but it takes about an hour or two before the headaches is gone.

    I have also found having exactly the same hours sleep (waking up via an alarm) everyday no matter when I goto bed has help as well.

    To summerise, These do work for me, not cure just make less frequent and milder, but you must take them religiously.

    900mg Asprin may help (but only if taken as soon as you sense a headache coming).

    Zomig may help when you have an attack.

    Please note Im no doctor, what works for me may not work for you, so please speak with your doctor. Im only telling you my experience.

    Here's hoping you the best of health.

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  • Posted

    Ihave been on Pizotifen for 7 years. Dr. has never suggested coming off them. When I was prescribed I had Sumatriptan prescribed as well. I still get migraines starting but the Sumatriptan stops them within half and hour! I put on over a stone and have never been able to lose it (I'm 54). Am considering coming off them to see if the frequency of migraines increase, if I lose weight (less appetite) and if I have more energy and less sleepy (or is it my age!!!) I would advise anyone with Migraines to ask to try Sumatriptan - it saved my life!
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