sulfasalazine for RA

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   I have seronegative RA and also crohns bowel autoimmune disease.   Had to come off Cimzia and Humira and couldn't tolerate methotrexate .   Has anyone just taken the sulfsalazine and no other drug for RA and it has helped with pain and inflammation?   Gastro Md doesn't want to try Remicade since I had heart palp / chest pain with first 2 biologics so not sure what the next step will be.   I am having gastric problems with the sulfa drug but just started it      Pain much worse since off cimzia 2 months ago

 

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  • Posted

    I was diagnosed with seronegative RA over 30 years ago. Hands like bunches of bananas, and could hardly walk. Diclofenac didn't help much, so my GP referred me to a Rheumatologist. Sulfasalazine was the first drug he tried me on. After two weeks, I could walk normally and my bunches of bananas turned back into hands again.cheesygrin  Now, I'm seropositive, take Leflunomide and a low dose of MTX. Not sure if Sulfa would work for me now as I also have Vasculitis so have Pred and Rituximab too. cry

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    • Posted

      Thank you for your response.   I hope your current meds are keeping you comfortable.  I stopped the sulfa drug as I felt very sick on it.  Possible doc should have started the drug more slowly, terrible headache, gastro problems so didn't want to continue.  Next month I am having colonoscopy so I am hoping to wait til after that to start another drug.   The gastroent. doc and the rheum don't always agree on the best treatment so that's another issue.   I am fearful of an IV drug since I got quite ill with the humira and cimzia

      and I have quite a low blood pressure.  Always something it seems.    bless you confused

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  • Posted

    Hi, I was diagnosed seronegative RA about 15 years ago and put on Sulfasalazine only, 2 grams per day, I sometimes took naproxen, but about a year a go inflammation started rising so was put Benepali as well, the Sulfasalazine worked well for about 14 years, with no gut issues.
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    • Posted

         I could be wrong but I think I started on 4 grams a day--1 gm 4x a day.   I did look up dosages and the gastro md ordered a much higher dose.  It seems that crohns requires a larger dose     Maybe I could have tolerated 2 gms.  Will talk to the rheum.  at next visit.  Haven't seen your posts in awhile so I was wondering if you were still ok on Benepali     I am 70 and not advised to take naproxen and other NSAIDS after age 65 I think, at least in US.  Plus with Crohns its not advised anyway.     I have 3 autoimmune disease and after awhile you start to think soon I will have another one   Hope not!!

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    • Posted

      Hi, yes I'm still on Benepali and it works great, with no side effects, I rarely take naproxen now, I don't know much about Crohns disease, would imagine it's not good, I have IBS and a redundant colon, meaning longer than normal with more twists and turns, tinnitus in both ears, apart from this lot I'm pretty much ok, ?, life keeps these problems coming, I made it too 42 years old before things went pear shaped, 65 now, I tend to see the cup half full, things could be worse I reckon, great talking.

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