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I have been on Sulfasalazine 2000 mg/day for 6 weeks. I went back to my rheumy for my follow up and happened to have a really bad flare up that day, so she wanted to increase my dose to 3000 mg/day and add the prednisone. I had the normal side effects, the nausea and upset stomach every time I would increase my dose, but I am feeling AWFUL on the 3000 mg/day. My nausea is absurd, I feel like I need to throw up every 5 minutes. I am so tired, especially today, I can barely keep my eyes open even with sleeping very well. I started noticing bruises on my legs and arms from just bumping into things and I normally do not bruise easily. I have NO appetite at all. YEsterday I had to force myself to eat something finally. I did paint my living room a couple days ago and felt OK, but the next morning I was in horrible pain and my hand/knee was so stiff i could barely move.
My rheumy said if the increased dose doesn't help then my next option would be MTX and I really don't know how I feel about that. I am scared of it, and honestly I enjoy my wine with dinner (or when I want it).
Has anyone else had side effects like these with the sulfa at 3,000 mg, and is it something that I need to get use to? The tiredness is the worst, especially at work, I can barely keep my eyes open and the pain is just bad. I am tired of complainging all the time about being inflamed, or in pain, or nauseous etc. I don't want to be a burden/annoyance anymore. What are your experiences with switching to MTX or just being on MTX,??? especially for those wine-o-fanatics like myself. Anything would help. The fact that it is starting to interfere with work is why I am reaching out.
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