Switched from lisinopril 10mg to hydrochlorothiazide 25mg

Posted , 8 users are following.

ve tried almost every class of BP medicine there’s is. Started with amlodipine...horrible side effects that sent me to ER 3x. Changed to atenolol, even worse side effects. Then I took hydrochlorothiazide 12.5 mg but it wasn’t enough to bring BP down. Finally found lisinopril and after 8 happy months, I’ve got the dreaded cough. Cough so bad that I couldn’t talk at work (I’m on the phone a lot for work).

Doctor decided to try hydrochlorothiazide again but at 25 mgs because she felt losartan would be too strong and side effects from that may hit me hard. 

Per the doctor, ok to stop lisinopril cold and I am now on day 3 of hydrochlorothiazide with high BP (139/95) and rapid resting heart rate (105). Headaches, dizziness and feeling foggy. Would this just be temporary since coming off one and starting another? I want to give it a few more weeks but I to feel better again. I’m almost ready to just deal with the coughing and get back on lisinopril so that my BP is stable.

Any thoughts?

0 likes, 32 replies

32 Replies

  • Posted

    These medicines are usually taken in combination.

    I don't like amlodipine either, but for some people apparently it works.

    Atenolol is unlikely to do much for your BP by itself, but it's good in small doses in combination.

    I take 25mg of HCTZ and it's great for me, but I need an ACE/ARB as well, in a small dose, to go with it.  Maybe with the HCTZ you can take a smaller dose of Lisinopril and do OK.

    If you're on HCTZ and get fast heart rate you may be low on electrolytes.  Have some potato chips or a banana or something, might help.  Otherwise if you have any atenolol around, that should lower the heart rate, it's really good at that - but don't use it to cover up electrolyte problems!

  • Posted

    I have been down the same road as you I have just stopped taking Nevibolol which I thought was ok until yesterday when I realised the swelling in my feet had reached my knees and I couldn't get my shoes on. Also my weight had gone up. Last night was my first without this drug and I had to visit the lavatory 5 times. When I took linispril I got the cough almost immediately but carried on with it for a month but the cough never went away. It took another 2 months before I got rid of the cough. I will just have to put up with my BP jumping around but I am not taking anymore except Indapamide. Life is for living and quality in it comes first. Dangerous but so is crossing the road!!!

    • Posted

      Indapamide is among the many drugs I’ve tried - it reduced my sodium levels to such an extent that I could hardly put one foot in front of the other!  So glad that it works for you.
  • Posted


    I too suffered all the same side effects as you, and I decided I would take my chances without the meds and side effects that were more likely to kill me!!

    However, I recently moved overseas and saw a local specialist who suggested I tried Carvedilol, which I did, and found there were no obvious side effects.

    my original GP put me on hypertension drugs based upon my reading on my blood pressure machine, and also based upon the GP’s electronic machine.  I have to say that here in the Philippines they all use the old type of manual blood pressure machines, and, on the 8 or 9 times I’ve been tested on three or four different manual machines, my blood pressure has been normal!!

    maybe some people are ‘allergic’ to new tech.

    • Posted

      Yes, the old traditional method of taking BP is the most reliable.  I was told by one of the electronic machine manufacturers that if, for instance, someone had a bit of an irregular heart beat (the method by which the electronic machines work) the machine would not record accurate readings
    • Posted

      Bazzank...you've tested just fine 8 or 9 times on 3 to 4 different manual machines. Perhaps when at the Dr., you are suffering from "White Coat Syndrome" which is VERY common. It's when one gets nervous in the Dr. office..& this causes bp to spike. Otherwise, the patient's bp would be normal. Did you know that bp can spike as many as 20pts in a Dr office??? It's true!.

  • Posted

    My first thought was that it could have been me writing your post!  I started off on Amlodipine - dreadful side effects, the worst it caused was a diagnosis of varicose eczema resulting from the ankle/lower leg swelling.  Four years hence and 7 other pills later, I have been on Losartan Potassium for some 3 years with no descernible problem except for it not really bringing my BP under complete control.  So I am faced with the prospect of another trial on another drug shortly, Heaven knows with what side effects.  I am an extra challenge to those treating me because I have just a

    sole kidney and Chronic Kidney Disease, and many of the drugs

    pose a risk to my remaining

    kidney function.  I’m at a loss for why your Dr considers Losartan being “too strong” for you - my pharmacist has told me that it is the drug about which he hears

    the least side effects from

    patients.  Admittedly, whilst I experience no side effects from a 50mg dose, any higher and I itch, particularly when adding another BO medication alongside!  Lots of good luck wishes - I really do both empathise and sympathise.

    • Posted

      Hi MrsO-UK Surrey...Idapamide is a different type of diuretic..actually it's better than HCTZ  but is usually found contained in a bp medication. In any event...for teresa06 to say her Dr. believes the Losartan would be too strong for her...that boggles me. Taking HCTZ along with something else DOES help reduce bp readings. It doesn't have to be the highest dose...start out low, then work up if necessary. The pharmacist was quite correct in saying the Losartan has the lowest side effects, but so does Valsartan. Both are in the classes of ARB's. My own Dr. prescribes Valsartan. It isn't any wonder she had a cough while taking LIsinopril. It's in the class of ACE's..which are known to cause hacking, dry cough. 1 in 4 get the cough while on ACE's. Honestly, I think she'd have better luck with a low dose Losartan along with HCTZ.

      I only wish the pharmaceuticals would come up with ONE bp pill..one that does the trick for everyone...very few side effects...very effective, etc...but that's dreaming isn't it. Sometimes the medications themselves make us sicker than the ailment.

    • Posted

      “Sometimes the medications themselves make us sicker than the ailment.”

      I so agree, Mike.  Isn’t it amazing though how some people can take a whole stash of pills without any problem?  Goes to prove how different we all are and let’s face it they only test these drugs on quite a small percentage of people when you consider how many of us are in this big wide world!  Even a recent change of eye drops prescribed made me itch all over.  I have decided that as  I was ‘made’ on a Friday when “the children were coming out of school”, I was a rush job with everyone dashing off early for the weekend!  

    • Posted

      MrsO-UK Surrey....good laugh!!!!!!!! I was born on March 13...oh but it was early SATURDAY morning!

      I do wonder at times why I have such rotten luck. I hate meds...& currently stopped taking the Tecta & other meds for the Gerd. The Gastroenterologist said it was ok to do this because they weren't helping anyway, but if I decide to start back..that was fine too. Or I could chew on Gaviscon. We're doing Gastroscopy May 17, so we'll see what's going on in the stomach. 

    • Posted

      MrsO-UKSurrey...thanks for the good wishes. I'm hoping the Dr. does find something. At least this way, we know what to do. If it's nerves (I do have a neurological problem) then that does present a problem for me because the nerves could do damage elsewhere as well. I must think positive though.


    • Posted

      Hello there. My mind is boggling over the fact that her Dr. stated that perhaps the Losartan would be too strong for her. Say, what!!??? Losartan is an ARB..not an ACE. ACE's are known to cause dry hacking cough, whereas the ARB's are not known for that. My GP usually prescribes Valsartan, which is also a member of the ARB family. If a higher dosage is first prescribed, then the patient is at risk  for side effects. Start with a lower dose, see how it goes, & if it works...great. If it's not quite doing the job...increase the dosage a little. The Dr. never gave her a chance...that's how I see it. BP of 139/90 is not high..that could be monitored for a while without meds. It may be considered high-normal, but isn't anything to worry about.

      A racing heart at 105 when resting certainly is cause for concern though. It isn't any wonder she's experiencing headaches, dizziness & a foggy feeling. 

      She made mention of perhaps going back on the Lisinopril, but what's the point? It interferes even with her job because of the cough., & the persistent cough certainly does put pressure on one's head. Think about it. This could be a cause of the headaches as well. I'd be very inclined to suggest to her that she get back to the Dr., & ask to try the Losartan...at a small dose..see how it goes.

    • Posted

      My feeling is that the lady should seek a second opinion from another doctor in the practice.
    • Posted

      So glad she saw another Dr. in the practise. Some people will actually suffer at the hands of a lazy doctor. Yes, I find this sort of thing to be lazy. Automatically, the Lisinopril is blamed for the cough. 

      Honestly, I do wonder at times how some people manage an M.D. license when their common sense isn't so common. A layperson could have said to that Dr. about checking her ears, throat, etc. But no, a lot of doctors think they know it all.,,& we know nothing. A BIG reason why I left the Dr. here in the city where Iive is a classic example of this. He was a young, cocky know-it-all..spent his time on the computer & I couldn't tell if he was listening to me or not. I got so fed up that I returned to my previous Dr's practice. So glad I did. I feel secure in his diagnosis& I can discuss anything & everything with him without feeling nervous. Also, I don't feel rushed. 

      WE are the doctors' employers...Don't ever let a Dr. say to you.."now dearie...don't worry about things" That's blowing the patient off. A Dr. should be explaining things in plain English so the patient has an understanding of what's going on. They have the right to know..it's their healthy, their body. 


    • Posted

      “A Dr. should be explaining things in plain English so the patient has an understanding of what’s going on.”

      Ah, but some doctors don’t credit their patients with being able to understand!

    • Posted

      MrsO-UK Surrey..I couldn't agree more! I have a friend who truly is a real dummy when it comes to anything medical. This may be a harsh thing to say, but she doesn't ask questions., doesn't ask when should she come back etc.etc. She has a longgggg history of having difficulty with bowel movements. Her doctor (the one I left) has prescribed this/that for it...nothing really works. He has put it down to a syndrome where people simply have difficulty with bowel movements. Get this..he has NEVER suggested she have a colonoscopy & she's 75 yrs of age!!!!! I mentioned this to her if the Dr. suggested colonscopy & she said..."Well, I'm not going to mention it to him". How risky!!!! She brews a sort of 'tea'...which means she has to stay in the majority of the day. "Once I get the plug out, I can go".she says. She could have an obstruction. Also, she just recently had a blood test...the 1st one since joining his practice..& she's been with him 4 years!!!!!!! Her potassium was on the low side, so she was eating bananas. I asked her when she goes back to see the Dr. for another blood test to see how the potassium levels were working out. She said.."I don't know"...& she didn't ask.

      Carlessness going on here for sure...but ignorance of the patient as well. 

    • Posted

      Some people would rather bury their heads in the sand, Mike, than risk hearing any news they dont want to hear.  We are all different, so each to their own, hey.
    • Posted

      My 63 year old friend takes  200 mg metropolol, 40 mg lisinopril, 5 mg amlodipine, 40 mg Lipitor, aspirin, 30 mg omeprazole, and a couple antidepressant pills . It doesn’t bother her.

      I struggle with 10 mg lisinopril and 7 mg carvedilol per day.

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