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Even with 150mcg of T4 it was as though the starter-motor wasn't there - I was particularly slow and very low in the mornings. My endocrinologist had to be persuaded to let me try T3 as he said the evidence for it wasn't there. Within the first few days, I could feel energy returning and mood improving. After a fortnight the depression was gone and hasn't returned at all in the following year. I now take 100mcg T4 and 20mcg T3 in the morning. I am now gradually reducing the anti-depressants that had been prescribed by my Doctor who saw me as just a middle-aged woman who couldn't cope with life and had delusions of having a thyroid problem.
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