Terbinafine Loss of taste

Posted , 110 users are following.

I had taken terbinafine for about six weeks for a toenail infection when my sense of taste pretty much completely disappeared over the course of 3-4 days.  I have a vague salty/bitter taste in my mouth, but nothing tastes of anything....sweet, salt, bitter...all gone.  I can put pure sugar on my tongue and not taste a thing.  That refreshing zing you get from toothpaste?  Gone.  Everything tastes grey at best, or just nasty at worst.

The infection responded well to terbinafine - I have about 4mm clear nail now, but I've decided to stop taking it as nothing is worth this cost.  I've switched to Loceryl lacquer but I don't even care about the nail anymore.  I just desperately want to be able to taste things normally again.  I can completely understand how this can cause weight loss and depression.  My advice would be to avoide terbinafine.

13 likes, 364 replies

364 Replies

Prev Next
  • Posted

    I'm so glad I found your post!  I also took Terbinafine for finger nail fungus.  I was wondering why I had such a metal taste in my mouth along with my taste buds being totally off!  Nothing tastes good at the moment sad  I stopped taking the Terbinafine about a week ago & nothing has changed yet as far as taste, etc...  From what I am reading in other posts my taste & the no metal in mouth will eventually resolve itself.

    • Posted

      Hi

      I'm 2 wks and a bit into  being off the tablets. No change in taste. Hardly eating. I've lost 9lb so far. 

      I would love a meal. I have wasted so much food. 

  • Posted

    Hi Jonathan and everyone else who has suffered from this awful drug. I started taking Terbinafine in the summer for a fungal nail infection and then stopped taking exactly 6 weeks after starting due to headaches, nausea, awful taste in my mouth and taste loss. That was 2 weeks ago and still no improvement as yet!  Your messages give me hope that this is not a permanent situation as it really is quite depressing. I have lost my appetite completely and when I have to eat, I do not enjoy anything. I have lost 3.5 lbs in 2 weeks!  I wish I had seen your discussion before starting on these tablets as I never would have taken them!
    • Posted

      I took it 6 wks for fungal nail. Stopped 4 wks ago. Taste just coming back. I lost 11lb. 

      Terrible drug. 

    • Posted

      Hi Diane. So glad to hear your sense of taste is finally starting to return -

      I hope you are feeling better for it. It's 5 weeks now since I stopped taking the tablets and although I am beginning to taste certain foods (generally spicy ones), my tastebuds are far from back to normal. Particularly unpleasant is anything containing dairy, eg milk, cream, ice-cream and worst of all chocolate!! Surprisingly, after an initial weight loss it has now returned to normal despite a very limited diet. Really hope we both recover soon! Clare

    • Posted

      Hi Clare. 

      My taste back to normal now. Yes I agree it was weird. One day I’d taste a certain thing and next I didn’t. 

      After the two week weight losses mine levelled out aswell. 

      Glad yours is returning. 

      Hope GPs tell the drug company how many have this side effect. Diane

    • Posted

      Oh I'm so pleased for you Diane. I'm approaching 6 weeks now and I'm finally getting there... I could taste every bit of my roast dinner today! 😊 Let's hope we're both finally cured! X

  • Posted

    Hi Jonathan21989!

    I had the exact same issue as you did with Terbinafine...about five weeks into taking it I completely lost my sense of taste. It's been about five days now and still I can't taste anything. Since I see you posted several years ago, can you tell me how long it took you to regain your sense of taste? Did you do anything to help along the process? Thank you so much! I thought I was going crazy; so glad to see someone else had the same experience as I did.

    • Posted

      Pardon me for replying. Mine started coming back at 5 wks.  Nothing you can do but stop the meds. 
    • Posted

      Thanks for replying, Diane! This is really so awful. So grateful to have this online community of people who know how horrible it is and have made it through. Did your sense of taste come back fully? That's my biggest fear in all this, that it will never be quite like it was before. Thank you again!

    • Posted

      Hi Gina 

      I lost my taste with this drug after around 5 weeks of taking it.  I stopped immediately, it took around 8 weeks for my taste to come back and it came back exactly the same as it was.  It's hard to believe you will ever be the same it's the most awful experience, but it will come back like it was before 😊

    • Posted

      Hi Allison

      Thank you so much for sharing. Glad to hear your taste came back fully. I will try to stay positive and know that however long it takes, it will at least not be permanent. This is so difficult though!

    • Posted

      Hello gina and everyone else suffering from this terrible drug. I’m a Norwegian woman (35 years old) who is living this nightmare right now. 

      I started taking Terbinafine for a toenail infection, after 30 days on the tablets my sence of taste was gone, replaced with this salty bittersweet nauciating sensation in my mouth. 

      I stopped taking the pills a couple days later. It’s been 8 weeks today since I stopped - I have lost 14 lbs (about 6 kg) due to the fact that I’m only able to eat crispbread with nothing on it sad I still have a sweet/salty taste in my mouth, sometimes a burning sensation as well. However I can say that my taste has returned maybe 15 %, I can taste some spices, a bit of umami and artificial sweeteners. This is driving me crazy, but I still hope my taste will return eventually, I’m just so impatient, I miss having a meal...

      I pray we all have our taste back in the end.

  • Posted

    I could start tasting salty items about 5 weeks after stopping this drug.  It has now been 8 weeks since I have not taken it & I can now taste salty & fianaly some sweet.  I would not recommend this drug to anyone!  Not only did it ruin my taste buds but I got a horrible coated & hairy tongue & it did NOT cure the nail fungus!!!  I am now seeing a dermatologist for nail fungal treatment sad

  • Posted

    Hey Jonathan,

    I have ringworm on my back that no cream has helped.Did you have any other side effects besides taste loss ? Im supposed to sta rt a 2 week regimen today. Does it only affect people who take it longer than 2 weeks ? Thank You !

Report or request deletion

Thanks for your help!

We want the community to be a useful resource for our users but it is important to remember that the community are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the community is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.