Testing while on birth control and Spironolactone

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I’m going to have a full pituitary blood panel done this Friday and between then and next Monday will be doing 2 24 hour urine tests, two saliva tests and taking dexamethasone and having bloods drawn next Monday. However, I’ve been on birth control since April and also Spironolactone as I was originally diagnosed with pcos. I’ve read birth control and Spiro can affect results and also cause you not to suppress after the dex test. Does anyone know if this is going to be problematic for me? Even if I stop the birth control, it’s been in my system for a while. I haven’t met my endo yet, just sent her my abnormal labs and she accepted to see me and her nurse gave me all the test instructions. I asked about the birth control and was told its fine to take. Anyone know what I should do? I was told by an old endo that birth control makes serum values inaccurate and falsely elevates. Do these drugs affect saliva tests? What about ACTH? Im going out of state to see this top specialist and don’t want to have it be for nothing if I’m told my results aren’t valid. Thanks. 

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2 Replies

  • Posted

    Hi Gina, I would advise that you wait to talk to your new endo as she will have up to date results.  Pepple with Cushings are sometimes mistakenly diagnosed with PCSO because some of the symptoms (especially excessive hairiness) are similar to those of Cushings.  Good Luck and let us know how you get on.
  • Posted

    Hi Gina. When I was being tested for Cushing’s I was on sprinalactolone too. But I was advised I needed to be off it I think 6weeks prior to testing. But I was put on a different mediacation by my doctor. I wasn’t on birth control but I could imagine it would be similar if it affects results u would need to be off it few weeks before testing.. I would think ur endo will do this with u. But it best to wait an see them an go on their advice. Good luck. 

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