Posted , 5 users are following.
I have to admit that I am going to play alittle stupid here but I want to understand .
OK so I have both of the "C" genes, does that come from one parrent or both or combination of both? My parents are not living so we cannot test. Our sons have one gene so that makes them a carrier and they could pass on to their children does our sons wife have to be tested ? What age does his children have to be tested
1 like, 6 replies
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haircrazydaisy mary89522
Posted
Hi Mary. You would have received one gene from your mother & the other from your father. If you look on the Canadian HH society website they explain all of the possible combinations. I was told that my son can't be tested until he is old enough to understand the implications of the disorder. Doctors will not test my mother even though she must have at least one gene - myself & siblings have two genes. I think you may find they are reluctant to test your son's wives. You can always ask, though. Confusing, isn't it?!!
haircrazydaisy
Posted
Sorry - your son's wife or sons' wives, I mean!!
sheryl37154 mary89522
Posted
The next best test for sons' wives is an Iron Studies test - every dr should do one for all their patients - it is a window to a lot of issues. However, if wives are still menstruating, the levels might not indicate the possibility of haemochromatosis (definitely won't if only a carrier), but there have been a few young women on this forum who have been found to have haemochromatosis while still menstruating.
Unless the mothers of your grandchildren have been found to have 2 genes, drs generally will not be in a hurry to order genetic tests on your grandchildren.
Golak mary89522
Posted
You have received a gene from each parent.
In order for you son to know what the chances for their children are , his wife also needs to be checked for the most frequent mutations.
Based on the results of the wife, decision is made whether to check the children early or not, if she is not also a carrier, there will be no need to check the kids. If she is, the children will have a 25%chance of being homozygous for the disease (they will show symptoms) .
mary89522 Golak
Posted
sheryl37154 mary89522
Posted