There is hope

This is what I've taken from the study site,

To evaluate a new investigational medicine for Ménière’s Disease. The study involves a study drug called OTO-104, and aims to evaluate the safety of multiple doses of OTO-104 in reducing the disabling attacks of dizziness/vertigo. New investigational medicines require clinical trials to test their safety and effectiveness. Each person with unilateral Ménière’s (in one ear) who enrolls in this clinical research study moves us one step closer to the development of new future treatments for Ménière’s. Clinical research is the key to finding new ways to prevent, diagnose, and treat Ménière’s and other inner ear disorders.

There is a gel they put in it this is to keep it in the ear and release over a period of time. I had hearing checked then ear slightly numbed, an injection goes right into inner ear, although slightly sore, I would rather put up with seconds of pain to dizziness anytime. 

The USA started the study and Britain were to do the phase 2 of it. This is the 3rd stage in which I am lucky to be doing the 2nd and 3rd phase. All reports will be sent back to USA to see how well it worked. I know it worked on me. If you Google menieres study for this you will get lots of information on it. I have researched a lot on this topic. I'm now looking to find other people who have done study 2 and how they feel now after it.

Hi, I would think this would be regular use, my Md came back 6 months after my last injection. The study was to see the amount injection given over the yr, I think some people had it 4 times a yr, 3 times a year or less. It definitely managed mine by having no symptoms of dizziness, sickness or fatigue which I all had. The tinnitus went after the 3rd injection. It came back 6 months after 4 th injection then 2 months after that the attacks came back. The guy I read about had it so severe, worse than me, he got better and mild attacks within 1 st injection and he got better and better as the yr went on. He called it the miricale cure. So that really is saying something that it helped him too. I had my life back last year, now I feel I'm back to anxiety, scared to go out and not being able to go out. This Monday coming I fill in forms to get study. Hopefully I will get injection within the next month. I will keep posts up how it goes for everyone. 

Hi Pat, I'm on the betahestimines but not working for me. When I went on trial the specialist asked if I was still taking tablets. I said no because I wanted to see if the injection would work on its own. I am not sure if other people was still on the tablets while receiving the injection. I sincerely hope too the trial ends soon and that this drug works for everyone else that has MD. being able to go out without worrying and enjoying life. I noticed last year I was free from it. When I have attacks my kids know what happens and will leave me to sleep it off. Feel for the kids as they see what I'm going through, and it's very hard to plan anything. 

I also really empathized with your comments about feeling for your kids. I try so hard to act like I feel well sometimes, but it's hard. I don't want to let my health prevent us from going out and doing fun things, but sometimes it is a consideration. I'm hopeful that with advances you're talking about, we can get past this! 

Hi your welcome. I didn't really change lifestyle as I suppose I was coming to terms with what I had. Before I knew it I signed up for the study as I was having frequent attacks. During the study I was still taking caffeine tea, smoking, living like as I did before a got md. I had no attacks in a yr and a half. I guess after that time the injection wore off and it came back.now I am looking at lifestyle, I am now going to cut out caffeine as a friend of mine spoke to a woman that cut this out and cured her md. I remember when I began to get symptoms like my ears were echoing and it was hard to hear people, I was learning Indian head message and to be honest that helped the tinnitus. As a complimentary therapist I've just read on this forum about reflexology helping. As I am a reflexologist I will try this, thankfully I have a few friends that do this too. I don't take a lot of salt or alcohol so I guess it will be giving up the smoking next. I don't know if it gets worse over the yrs or if that's us for life having this but the injections were a god send. There has been many thoughts ran through my head, do I have this due to another reason, like I wouldn't say I have really looked after my body is it time to do this to help with md. at this moment I'm just looking forward to the study again to get more info which I will no doubt get on Monday. I will keep everyone posted how it goes. Menieres study uk has info about the injections.

Hi Ian I think it is, as it was a steroid I was on for the year. Mines has come back more frequently this past month, but thankfully looking forward to next injection. After an attack I feel so tired and sleep for hrs, I don't take that much salt in my diet and just changed to decaf tea. Hoping it makes a difference. I hope so too Ian had a normal life last year praying these injections are the answer to all sufferers.