Treatment with other immunosuppressants
Posted , 6 users are following.
Dear Eileen/other foru musers,
do any of you have any information on outcomes of treatment with mycophenolate for atypical PMR and GCA to help reduce the reliance on pred?
Many thanks
Heron82
0 likes, 1 reply
EileenH Heron82
Posted
It isn't recommended in the 2015 Recommendations
https://www.rheumatology.org/Portals/0/Files/2015%20PMR%20guidelines.pdf
but this is a very small study (3 patients)
https://link.springer.com/article/10.1007/BF03325257
which concluded
"mycophenolate mofetil may be considered a steroid-sparing agent in elderly patients with GCA but, before results of controlled trials become available, MMF may be considered only for patients who do not improve or stabilize with conventional therapy, or in patients for whom reduced steroid dosage is highly recommended."
There are no clinical trials - so it is off-label use.
You might find this thread of interest:
https://patient.info/forums/discuss/mycophenolate-for-pmr-338538