UC Medication Combinations.

Posted , 4 users are following.

Hi everyone. Just found this board and hope that someone may be able to answer my question(s). My husband was diagnosed last September and had a course of steroids which has limited effect. Azathioprine didn't agree with him at all and he reacted badly. During the last week of steroids he had a hospital appointment and the doctor asked him to try maselazine enemas. Within 3 days he was much improved and this continued until last week whe on another hospital appointment he was told to come off the enemas and start a course of methotrexate. He has been off the enemas for a week now and he is in pain and has started to bleed. He was told that the methotrexate will take up to two months to have an effect, so to my mind he could be left without any effective medication for up to two months. My question is can he take the enemas as well as the methotrexate ? Does anyone know why they would make him stop a medication that was working? At the moment he is showing all the signs of heading towards another flare.

Thanks for reading, sorry if a bit long winded.

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4 Replies

  • Posted

    Hi I don't know why they should stop enamas if they worked I was on them for months at age 18 and steroids etc. But I lost 4 pints of blood in 1 year and had to have total large bowel removed at age 19 I'm now 53 it saved my live and that pain before was terrible . I would ask why they would take him off enimas etc and push for second opinion from the hospital or another hospital doctor .

    Also it did not ruin my life the operation it gave me life. But do everything u can first to see if it works I hope this helps

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  • Posted

    Not long winded at all!!! I would have him or if you're able to speak for him - to contact the nurse right away or to contact the gastroenterology department and his specialist rather than leave it.  I was told that the 'meth' could take 3 months to be effective though I have it more for the enteropathic arthritis along with the other bits of arthritis I have but I'm also on 'Aza' which I can tolerate.  I also have the pentasa suppositories which I take almost every night at the moment to keep the bleeding down and have the mesalazine enema for when i'm really bad which also does the trick.  Please please don't leave it........

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  • Posted

    Thanks for your responses. Fluff I didnt leave it and he has now spoken to the IBD nurse who said there is no problem going back on the enemas. As you say laciaboots it does beg the question as to why his doc asked him to stop the in the first place. Hopefully he can get back on a bit more of an even keel. Thanks again for you kind and helpful replies.
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  • Posted

    Hi, not really sure why they would take him off the Mesalasine if it was working for him. Perhaps you need a discussion with his Doctors to get clarification. 

    Hope you get it sorted out quickly x 

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