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urticaria treatment

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chris29126
chris29126

hi i just recently have been diagnosed with hives and have been prescribed perednisolone and fexofenadine by my gp but reading the leaflet it say do not take if yu have heart or liver disease well ive had both i had a heart attack 3 years ago and have a stent fitted and have had hepatitis c but i have been treated for it and have got rid of it but dont know weather to carry on taking this medication  please could someone give me advice thanks  

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2 Replies

  • siobhan37552
    siobhan37552 chris29126

    Posted

    Hi Chris,

    I would speak to your pharmacist to see what they say. Funnily enough I was asked when picking up my fexofenadine the other day if I have noticed any changes to my heartbeat. If I had an underlying condition or history I would be very cautious. There are lots of antihistamines out there, I'm

    Not sure about the predisolone. I had this too in several occasions. They only let you take short courses. I must say side effects for me weren't great. But I desperately needed the break for this horrific condition.

    All the best.

  • January20
    January20 chris29126

    Posted

    Hello,

    I've posted in depth on Hive so cut and pasted here (read all of my posts):

    Basically, hives are due to release of Histamine so antihistamines are the #1 drug, which may need to be taken in excessively high doses (up to 4-fold recommended dose). So block the histamine using nonsedating-2nd gen drugs like citirizine, loratidine, etc in addition to 1st-gen antistamines like hydroxyzine, benadryl, if 2nd gen don't work. Steroids may need to be started and tapered- steroids help with the angioedema and histamine release. You might need to be on a higher dosage of doxepin.  I take 1st gen drugs q3-4 hours around the clock (I set an alarm) when hives are present in addition to all the other drugs which helps tremendously- takes 2 full days for the hives to disappear if all over my body and less time if just mild presentation. 

    In the USA, an allergist is the specialist of choice because hives is a systemic problem that presents as itchy skin but is not truly a derm problem. A Rheumatologist would be an alternative since they also deal with autoimmune conditions as do dermatologists.  Yes, the disease sucks but you have to learn to live with it because what is the other option..... death? Hives will not defeat me.

    Best

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