Venlafaxine 375 mg when will it work?

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looking for people that are in the same boat as i am..

  1. any success stories for 375 mg?
  2. how long did it take?
  3. do we give each dose 4-6 weeks to work
  4. with every increase there is always a window of 2-3 days i feel myself getting better (appetite, less heaviness, music) but then i crash back again without any cause... is this normal?

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  • Edited

    Hi Timmmm

    I have just increased from 225 to 300 and I am 5 days in and today I have noticed a very small uplift to my mood and my anxiety is a little less. I have been on 375 in the past and went as low as 150. Every increase seems to take 1 to 2 weeks to get me back to a state I call normal and get on with my life once more. So I keep telling myself "I will get better" or "I will be normal in a few days".

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    • Posted

      Hi Karl,

      Thank you for replying!

      I'm now in my fourth week and can say I finally have some improvement that seems to be staying. (so far) I seem to be a bit more present have somewhat of an appetite again. Still not as well as I know I can be. I'm just very curious to see if I will further improve. I do everything I can to keep it going in the right direction.

      ***Do you know if once the improvement is felt then that's it? Or will it further improve??

      Sorry just feel so desperate to feel better...

      With every upgrade I would have 2-3 days where I could feel myself improving and then I would crash again no trigger. I have been in depression already for over two years now and am soooooooooo ready to finally be relieved from the monster. Lexapro my miracle drug dropped out on me. Tried paroxetine no effect and I now have been building on venlafaxine since August (so over 5 months now)

      It is exactly what you say! you have to keep telling yourself that this is a state of mind. And that depression is lying to you and that your own view has been distorted. I know rationally speaking that my life is great I just wish that I can finally particpate in it again and not watching it all flash by from the f*****g side lines.

      Thank you for the response and wish you a speedy recovery to the good side of the world again. 😃

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