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I've heard that venlafaxine is very good for lifting severe depression. I was prescribed it before but didn't take it due to the side effects. I took one 37.5 tablet and side effects were awful. I heard that the XL version does not produce so many side effects. Does anyone have experience of both? Which did you find best in terms of side effects? I have since taken fluoxetine and lofepramine which did not work at all. I have treatment resistant depression and need a very effective tablet. Will not take mirtazapine due to weight gain but I read a lot of posts on this site about weight gain with venlafaxine which worries me. Has anyone taking this tablet experienced weight loss or not experienced weight gain? I don't want to take anything that will cause weight gain as I put on 2 stone in 2 weeks when I took Amitriptyline and it took 1 year to lose the weight, so don't want to go through that again. Its very difficult finding the right medicine. It seems like the ones which produce the worst side effects are the most effective. I experience no side effects with fluoxetine or lofepramine but they did not work either. On the other hand, Amitriptyline had a lot of side effects to begin with but worked very well for depression, although they stopped working after 2 years. Any advice welcome. Thanks.
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