Venlafaxine ir v er

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Hi.

Can anyone give me any feedback of their experience switching from IR to ER.

I have been changed from 150ir to 150er and Mirtazapine 15mg added in and feel shocking until the afternoon then dip again at night? 

Many thanks

Chris

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6 Replies

  • Posted

    I've just started on this drug so not much experience, however I do know that the ER version reaches peak concentration in your body 5 to 9 hours after you take it, so it could just be your body re-adjusting after being used to an immediate 'hit' from the IR version.

    Also, I hope you are taking the mirtazapine at night! I was on 15mg for six months but found it too sedating. It was brilliant at helping me sleep though! I think I ended up taking it about 8pm to try and counter-act too much grogginess the following day.

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    • Posted

      are you about to? Well I won't lie - it was dreadful! I had terrible withdrawal (night sweats, waking up in a panic, increased anxiety) but I think the GP tapered me too quickly. take it as slow as you can and hopefully it will be ok! I should add that after a couple of months I was ok, but it wasn't pleasant while it lasted. Good luck!

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    • Posted

      Thanks for the reply. I think you could be right with what you’re saying about my body adjusting. Only started taking the Mirtazapine this week but I do take it around 9.30 pm and it’s great at getting me to sleep but do feel drowsy next day. 
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  • Posted

    When I was on Venlafaxine I found they weren't working too well so decided to cut back on them. My Dr gave me Mirtazapine to help. What a huge mistake, I was walking around in a bubble and feeling really unwell. Speaking to other people they felt the same. Another name given for this mix is 'rocket fuel.' After 4 days I went back to my Dr and came off the Mirtazapine, would never take these two medications again. I'm still on Venlafaxine 150mg first thing in the morning. Coming off Venlafaxine is very difficult and if I had known more about this antidepressant I would never, ever have taken it.

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    • Posted

      Hi Shirley,

      I’m only taking 15mg but keep having waves of bad thoughts/dread and feeling awful. Think I’m going to stop taking them and see about increasing the venlafaxine as this has worked for me in the past. 

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