Venlafaxine stopped working??? HELP PLEASE

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I am feeling like I can't carry on at the moment.

I have had severe anxiety and depression since giving birth to my daughter 4 years ago and it seems to coincide with my hormones during the month.

Since December 2015 I have had to increase my venlafaxine 5 times.

I was initially on mirtazapine 45mg then venlafaxine was added on for a year at 37.5mg this was great for the first year but now Every few months I am having relapses before my time of the month and the venlafaxine has to be increased by 37.5mg.

I am now up to the top dosage of 225 mg 4 days after increase and top dosage of mirrazapine 45mg and just feel like giving up and that I am running out of options, I am taking 4 different tablets of Ven throughout the day.

The doctor thinks I have PMDD but could it be that the venlafaxine is just not working well enough to mask my major hormone issues which it did successfully for a year.

Any advice please ???

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  • Posted

    Not sure if this is similar but I think you can suffer for about 3/4 weeks after each increase. I was put up to 187.5 a week ago and feel terrible today. I'm also on 3 X 5mg of Buspar during the day. It's hard but we've to try and get through the first few weeks X

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