Wanting off this med

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I've been on a few meds over the past 5 years for GAD, bouts of depression and bad health anxiety...took my doctor 3 years to realise lustral (sertraline) wasn't working and switched me to cymbalta (duloxetine) 7 months ago...no improvement at all. I was tapered off cymbalta and put on mirtazipine 15mg 6 days ago...ive felt like a zombie since the first night taking them..sleepy, irritable, spaced out and dizzy. I'm considering just taking half of one tonight and phone my therapist tomorrow and say I want off this.. .she will no doubt try to get me to persevere for another 2 or 3 weeks but I don't want to. She offered me venifexaline as a choice before she put me on this stuff. She was also talking about trying pregabilin but I'm not sure I want to go down that route. I've done cbt 3 times and even paid for hypnotherapy.. .now I am leaning towards trying ketamine or a trip on psilocybin mushrooms or lsd to try to find a root cause to my issues. I'm not reccomending any of the above drugs to anyone...do some research of your own.

Anyone else get this hangover numb effect from mirtazipine when you started? Any info would be appreciated

Thsnks

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7 Replies

  • Posted

    Hi Rob

    i was on mirtazapine 15mg for a year ,it did take a few wks for side effects to wear of ,but it never helped with my depression at all in fact it caused me to have anxiety as I never suffer anxiety until I was used this medication. I'm now in withdrawals of mirtazapine,it's heading to 7wks from I was switched from mirtazapine to a different anti depression... no one but you can decide if you want to stay on it and give it a few wks to see if side effects settle down but once you have been on it 2wks that's it into your system and withdrawals are horrible (well for me they are) 

    everyone reacts different to mirtazapine some people thinks it's a life saver but for me all it done was give me a full nights sleep but did nothing for my depression 

    good luck 

    kaz

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    • Posted

      Thanks Kaz for the rest reply. Yeah I think I want off this before I need to taper slowly. How have you been since you come off the mirtazipine?

      Thanks

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    • Posted

      Hi

      as i said I never felt great while on mirtazapine when doc took me off the just over 6wks ago the 1st few days I felt great then 3rd day I was hit with all the withdrawals thought I was losing my mind ... last 3 days seems to be bit better. Yes definitely have a think about it and if you want of them get of them asap before they get into your system, if there is anything I can help you with just send me a private message...

      kaz

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  • Posted

    Yes, persevered but still no go. Now trying to get off it. Read up about that before you commit to it. I think ketamine is showing great results in Australia where they are streets ahead. Oxford in uk is doing trials.  Also theres thevTMS clinics opening in uk now. Its been approved by NICE. Some good results.  Do some research into these. Good luck
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    • Posted

      Thanks Ann, yeah I mentioned alternatives to "big pharma " meds like ketamine to my therapist and she looked at me as if I was actually mental..i told her about all the promising research that's been done and even to check it up herself. She says she does want to help me but it seems only on her terms.

      I've got hold of 500mg of ketamine shards and I hear that a half mg per kilo of bodyweight is the recommended dosage (so around 40mg for me)..but that's through IV over a period of 25 - 35 mins. So I'm guessing orally I'd need 50-60mg. To me there seems to be too much strong evidence to disregard ketamine completely.

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    • Posted

      What's TMS? as never heard of that.I know ketamine is used as a horse tranquilliser,and also as analgesia for massive pain relief,when morphine not adequate,without giving too high dose that would suppress your respiration,but didn't know it's being used for depression and anxiety conditions in Australia with good results.

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    • Posted

      Yes, its on this site, a patient is foing to trial,it.

      TMS is a new one from USA with success there,  they hold a magnetic instrument over your head each day for six weeks and it lifts depression.  Only not available on nhs yet. You can read about it on website.  It really helps people who havent had remission from medication.

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