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What is my Stage of Hepatitis B with Elevated SGPT, SGOT and high HBsAg titre level?

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CoooolGuy
CoooolGuy

I am 40 years old male with BMI (body mass index) of 20 and patient of Hepatitis B. I was first diagnosed with HBsAg Positive in 1998. At that time Doctor said, it is just carrier and advised me to spend life as normal. During 2007 to 2009, I went through couple of dental problems and I did not know that I got infected with Hep. D (Delta virus) through dental. From 2007 to 2012, I did not go through any lab test. I came to know in 2012, when my lab test of Anti-HDV (antibody Hep. Delta Virus) came as Positive. After taking some herbal medicines for one year, my lab test of Anti-HDV became Negative in 2013. My ultrasound is normal and all other lab tests are normal. My HBsAg titre level is still high at 2069, SGPT (ALT) is 56, SGOT (AST) is 37, and Platelets in CBC is 140 x 10E9/L. My Cholesterol level is on the upper limit of normal range.

What does these high SGPT, SGOT and high titre level indicate about my condition? Does it indicate any liver problems?

Is my Hep. B on carrier stage and under control?

Should I go through any medications or more lab tests?

Your advices and feedbacks would be much appreciated.

Since last two months, I am having more burps than usual, and my body digests food more quickly, I feel hungry within three hours after lunch/dinner and I always have to eat some snacks every two to three hours. But my weight is not increasing. Please also explain, is it good for my health or not?

History of my Lab Tests results are as follows:

In 2013:

HbSAg: Positive (2069)

Hep. B Surface Antibody: Negative

Hep. B Core Antibody Total: Positive (0.006)

Hep. B Core Antibody-IgM: Negative (0.052)

Hep. Be Antigen:Negative (0.124)

Hep. Be Antibody:Positive (0.005)

Hep. Delta Antibody:Negative (1.247)

Hep. B-DNA by PCR: Not Detected

Hep. D-DNA by PCR:Not Detected

Platelets (in CBC): 140 x 10E9/L (Normal Range: 150 x 10E9/L to 400 x 10E9/L)

SGPT (ALT):56 IU/L (Normal: less than 45)

SGOT (AST):37 IU/L (Normal: less than 35)

ALBUMIN:4.6 g/dl(Normal: 3.5-5.2)

GLOBULIN:3.2 g/dl(Normal: 2.9-3.1)

A/G RATIO:1.4 (Normal: 1.2-1.7)

Vitamin D:15.5 ng/mL (Normal: greater than 30 ng/mL)

Serum Cholesterol: 180 mg/dl (Normal: less than 200 mg/dl)

LDL-Cholesterol: 108 mg/dl (Normal: less than 100)

VLDL-Cholesterol: 22 mg/dl (Normal: less than 30 mg/dl)

Serum Calcium: 8.6 mg/dl (Normal: 8.6-10.2)

Serum Sodium:147 mmol/L (Normal: 136-145)

Serum Ferritin: 92.9 (Normal: 28 to 365)

Serum B12: 533 (Normal: greater than 201)

Serum Potassium: 4.3 (Normal 3.5 – 5.1)

Serum Chloride: 104 (Normal: 101 – 112)

Glucose Fasting: 80 (Normal: 65 – 100)

Hemoglobin A1C: 5.0 % (Normal: 4.3 – 6.1)

Serum Triglycerides: 111 (Normal: less than 150)

Total Bilirubin: 0.6 (Normal: 0.1 – 1.2)

Direct Bilirubin: 0.1 (Normal: 0 – 0.2)

Indirect Bilirubin: 0.5 (Normal: 0.1 – 0.8)

Gamma GT: 26 (Normal: less than 55)

Alkaline Phosphatase: 69 (Normal: 45 – 129)

Total Protein: 7.8 (Normal: 6.4 – 8.3)

Serum Alpha-Fetoprotein: 3.6 (Normal: 0.5 - 5.5)

In 2012:

HbSAg: Positive (2117)

Hep. B Surface Antibody: Negative

Hep. B Core Antibody Total: Positive (0.009)

Hep. B Core Antibody-IgM: Negative (0.070)

Hep. Be Antigen:Negative (0.124)

Hep. Be Antibody:Positive (0.002)

Hep. Delta Antibody:Positive (0.251)

Hep. B-DNA by PCR: Not Detected

Hep. D-DNA by PCR:Not Detected

Platelets (in CBC): 157 x 10E9/L (Normal Range: 150 x 10E9/L to 400 x 10E9/L)

SGPT (ALT):67 IU/L (Normal: less than 45)

SGOT (AST):42 IU/L (Normal: less than 35)

ALBUMIN:4.6 g/dl(Normal: 3.5-5.2)

GLOBULIN:2.6 g/dl(Normal: 2.9-3.1)

A/G RATIO:1.8 (Normal: 1.2-1.7)

Serum Cholesterol: 156 mg/dl (Normal: less than 200 mg/dl)

LDL-Cholesterol: 103 mg/dl (Normal: less than 100)

VLDL-Cholesterol: 13 mg/dl (Normal: less than 30 mg/dl)

Serum Calcium: 9.5 mg/dl (Normal: 8.6-10.2)

From 1998 to 2007:

HbSAg: Positive (the title level increases from 88 to 175 during this 10 years)

Hep. B Surface Antibody: Negative

Hep. B Core Antibody Total: Positive

Hep. B Core Antibody-IgM: Negative

Hep. Be Antigen:Negative

Hep. Be Antibody:Positive

Hep. B-DNA by PCR: Not Detected

SGPT (ALT):between 16 and 21 IU/L (Normal: less than 45)

SGOT (AST):18 IU/L (Normal: less than 35)

Platelets (in CBC): 190 x 10E9/L (Normal Range: 150 x 10E9/L to 400 x 10E9/L)

0 likes, 3 replies

3 Replies

  • temg74968
    temg74968 CoooolGuy

    Posted

     I as a professional, normally do not make a diagnosis or consults thru the internet without a thorough history and physical exam. While looking for a conversion factor for a laboratory result, I clicked upon this forum. To answer your query, pasted is an article "approach to HbsAg positive patienst"

    http://depts.washington.edu/hepstudy/hepB/mgmt/hbsag/index.shtml\

    Chronic Inactive Carrier of HBV

    Chronic inactive hepatitis B infection is defined as persistent HBV infection of the liver without significant ongoing hepatic inflammation and necrosis[12]. Blood tests on such patients are typically show four characteristic features:

    HBsAg positive for longer than 6 months

    HBeAg negative, anti-HBe positive

    Serum HBV DNA less than 2,000 IU/ml

    Persistently normal hepatic aminotransferase levels

    The "chronic inactive carrier" state may persist for decades. Patients who remain in this phase of infection have lower rates of disease progression and hepatocellular carcinoma[13]. Generally, antiviral treatment is not indicated for such patients, unless histologic or clinical signs of cirrhosis are present[12].

    More important to the practioner and to the pateint is the liver function test, and In your case, even with the slightly elevated Sgpt,, is no reason to be alarmed.

    I hope this article alleviates your fears.

  • king22913
    king22913 CoooolGuy

    Posted

    Hello coooooguy, please can I know what herbal drug you took, it might help someone please, thanks
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