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When does sertraline actually kick in?

Posted , 55 users are following.

zoe111
zoe111

Hi to you all,

I've had panic disorder with agoraphobia for over 20 years. I was on the highest dose of Duloxetine for approximately 10 years, but recently my GP took me off this, as I was beginning to have many episodes of panic attacks.

I started taking 25mg of sertraline 18 days ago. Since then the GP has raised the dose to 50 mg and then on day 14 of taking sertraline she raised it again to 75mg. I wondered if anybody knows how long it takes to get in to the system. I currently feel more anxious and highly agitated. I'm finding it hard to leave the house. Any advise would be welcome, as would any information on this medication. I need to start feeling better soon, as I am self employed and need to earn some money. This is also adding to my anxiety!

Thanks!

7 likes, 106 replies

106 Replies

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  • james61783
    james61783 zoe111

    Posted

    Hi there

    I am on 50mg. It can take up to 18 weeks before you fully see it working. I have been on it for 12 weeks and still experiencing side effects. Don't get me wrong, the side effects are not as bad when I first started on them but you do still get days being anxious and the insomnia is a right bitch still.

  • Strattylass
    Strattylass zoe111

    Posted

    Hi..I have just found this post and I'm so glad I did. I have recently been diagnosed with depression and it's been a bit of a nightmare with meds. I have been on fluoxetine 40mg for several years for my PMT but this wasn't helping my depression. My doctor starting me on mirtazapine and it really did make a massive difference, I felt like I had me back even after just a few weeks of taking it. The only problem was I was piling on weight. I put on nearly 2 stone in 6 weeks so I came off it. My doctor has now put me on sertraline 50mg but after a month I am still terrible. I'm not sleeping..I am more anxious then I've ever been, I'm not going to have any skin left on my lips and around my nails. I am constantly tense and I can't relax at all. I am having mild suicidal thoughts too which I didn't even have before I started taking AD meds. I don't know what to do, I am getting worse daily and I am a single parent of 3 young kids and I have 2 businesses that are all being effected. Any advice would be much appreciated.
  • sharon36528
    sharon36528 zoe111

    Posted

    Hi zoe i to have started zoloft started with 25mg now on 50 as of today i think expect increased anxiety till it kicks into systom and it can take a couple of weeks though we r all different good luck
  • weenett
    weenett zoe111

    Posted

    How is everyone now?
    • Riab
      Riab weenett

      Posted

      Hi weenett,

      I’d love to hear how everyone is doing now too. No one has replied yet. How are you doing?

  • sandra06824
    sandra06824 zoe111

    Posted

    Hi im new here and i was put on sertraline 50mg yesterday as my depression has come back really bad this time round i was wondering if any of u got really bad head aches at the begining

    • weenett
      weenett sandra06824

      Posted

      Yeah the head aches are normal they ease after abt a wk or so
    • sandra06824
      sandra06824 weenett

      Posted

      Thank you i was starting to worry a bit so thank u at least i now know that it is normal
    • weenett
      weenett sandra06824

      Posted

      Dont worry they can b quite intense huh? Sert can throw some grim se's our way in first days but all should mostly settle in a few days. Other than headaches how r u finding it?

    • sandra06824
      sandra06824 weenett

      Posted

      Yea other than head aches and not wanting yo eat im finding it ok i know it takes a while to work.
    • weenett
      weenett sandra06824

      Posted

      I cant eat either im surving on drinking coke and milk x
    • Riab
      Riab sandra06824

      Posted

      When I restarted Zoloft, I felt depressed for a few weeks. This is my about my fifth week and I feel the depression has lifted, but still have anxiety. How are you doing now? Please reply.

      Thanks.

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