Why does Thyroxin make me feel worse?

I think that your energy levels won't pick up until at a least a month after starting on thyroxine. I must say I find it strange that you are getting a negative response from them. I am classed at prediabetic and the only reason this picked up was because I was suffering from tiredness. My hypothyroidism has been stable for approx 8 years now. I am still tired although trying loose weight, I am not obese but liable to become so unless I take care. My parathyroid levels are also high and I await an interview with an Endocrinologist . I am a woman of 73 and have pretty fit and active up to now. M

Thank you for the encouragement. I felt fine until I took Thyroxin! Maybe I have to stick with it for longer as you say. I only have to take one and I feel bad quite quickly. I think I might ask for another blood test for Thyroid and see if it is still too high.

I wonder when you are taking the thyroxine. I take mine in the morning 30 mins at least 30 mins before breakfast. It is often recommended to take them last thing at night,again away from eating anything. I don' t think they should be taken with any other medications. My husband also take Tamosulin but takes it at a different time from his thyroxine.It is a real bind sometimes trying to know what to so for the best.M

Hi. I think mvwaugh, may well have hit the nail firmly on the head! Thyroxine should ALWAYS be taken seperately from other medications. It's ok! You are not daft! Most of us are not told this cos most docs don't know! In fact my doc said swallow the lot together, and I'm taking meds for 4 different conditions!Also know that you should not take thyroxine within at least an hour of food (either side), and definitely not within an hour of dairy products as this interferes with absorption. Definitely go back on them, untreated Hypothyroidism is as dangerous, (if not a lot more more) than type 2 diabetes. If you put the cosiderations I have mentioned into place, and you still feel ill, then go back to your doc and explain. Write down what you have told us, and you won't get tongue tied when you are there, (we all know what that is like, it's part of the condition.) Good luck!

Thank you so much mvwaugh and pippa. I too am taking four other kinds of medication - all in the morning with Thyroxin! I will take it later in the day - an hour away from food and see how it goes. Given that I felt well and didn't suffer any symptoms made the effects of Thyroxin seem less tolerable. I will also note the point about dairy. Actually my Doctors are generally very helpful and I have learned how to "manage" them over the years! Interesting though to read in the medical notes for these drugs that they all interfere with each other. The makers of Levothyroxine for example, state that the Doctor should be advised if you also suffer from high blood pressure, diabetes and in particular, if taking Metformin! The makers of Metformin advise against taking ACE inhibitors (for blood pressure) or Thyroxin. It would require a very special GP to understand these combinations I am sure.