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Why PMR and my other autoimmune issues I've had? A possible answer.

Posted , 15 users are following.

Danrower
Danrower

I listened to a podcast "TED Radio Hour", titled "Hardwired": which hypothesized that early childhood stress has a very significantly increased statistical causal effect resulting in many disorders, including Autoimmune, throughout life.

For me, this answers a lot of questions I've had.

Here are the topics which, when googled, will take you to the Podcast and scholarly article:

TED Radio Hour:Hardwired

Cumulative Childhood Stress and Autoimmune Diseases in Adults

I will follow this post with a separate post with the links, for your convenience, but they will probably be blocked until reviewed by Moderator.

This was Very significant for me, as it answers a lot of questions, one of which :

" How did I get this host of Autoimmune disorders?"

Might burn an hour of your time, but you're on this forum, Right?

Thanks for the look-see, and good luck.

0 likes, 15 replies

15 Replies

  • Silver49
    Silver49 Danrower

    Posted

    Thank you, Danrower. I'd be very interested but I'd need the link, please.

  • EileenH
    EileenH Danrower

    Posted

    Can't find it with google. Send me the link as a pm please?

  • EileenH
    EileenH Danrower

    Posted

    Hopefully, here you are:

    https://www.npr.org/programs/ted-radio-hour/545024014/hardwired?t=1552337575994

    I could find the article:

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318917/

    • Danrower
      Danrower EileenH

      Posted

      Eileen,

      Yes! Thanks for posting.

      How were you able to post the links ? I was unable. I did send you the links, pm.

      By the way, so sorry to you about the b-word, I hoped that you would be clear of the effects. I suppose that none of us are immune to the political, national and policy decisions our voting public makes, and how our elected leaders direct our nations.

      Kind regards,

      Dan

  • Harrie4
    Harrie4 Danrower

    Posted

    This is great: what an awesome community!

    Two more cents: there are measures that very helpful wrt mitigating he impact of childhood trauma -- which can begin in utero. Bessel can der Kolk (Body keeps the score) and Peter Levine offer sensible approaches and practical tools. Easy to find via youtube and the interwebs.

  • artfingers
    artfingers Danrower

    Posted

    I guess I would wonder then why all my 4 siblings are fine, yet I was "blessed" with PMR and other autoimmune diseases. Thanks for sharing the link!

    • Danrower
      Danrower artfingers

      Posted

      I believe in science, and that all things have a scientific explanation. We think we have "majority" knowledge of the known medical universe. As wondrous as our scientific and medical knowledge is, we have more to discover and learn than we have already learned. The biochemistry of our bodies....a monumental frontier for research. This is just a piece in the medical causal puzzle, and might not be for some.

    • catherine34621
      catherine34621 artfingers

      Posted

      artfingers. I am just opposite from you, I have three sisters, one fine health wise, of my other two, one has osteo-arthritis, the other one has PMR and I have GCA, strange world aint it! I think Danrower ,you may have something here.

  • Joydeck
    Joydeck Danrower

    Posted

    I am sceptical of the stress connection, attributed over the decades to many an ailment. Notwithstanding, stress likely encourages self-defeating behaviour that leads to ailments. For instance, lack of healthy food, exercise, sleep, sunlight, social interaction, etc.

    I likely inherited my PMR from mother, rest her soul.

    • EileenH
      EileenH Joydeck

      Posted

      Stress affects the immune system - that is very well established. You don't "inherit" PMR, it isn't a genetically carried disorder in the way cystic fibrosis is - but generally carrying Scandinavian genes does predispose you to things all coming together and resulting in an immune malfunction. Not the same thing at all.

    • Danrower
      Danrower Joydeck

      Posted

      Joy,

      Did you listen to the third segment of the TED talk listed previously in this thread?

      It's what brought me to posting these links.

      This is inexact science, with respect to nurture v. nature, because we are primitive in our knowledge. But this unpleasent visitor, PMR , is of scientific result, not mysticism or luck. There is reason and scientific answer, we are just living in a time where it is not yet understood.

    • Joydeck
      Joydeck EileenH

      Posted

      Of course, PMR is not lock-step genetic like haemophilia.

      Chronic acute stress has, of course, a wide range of affects. This abstract from a May 2018 study is one of many:

      "Nazi concentration camp survivors have been shown to have excess mortality in the first 20 years following their release. To determine if this excess persists, Israeli civil servants were studied. Mortality of camp survivors and of other post-war European immigrants was compared 20–41 years following World War II. Using survival analysis and proportional hazards models, no difference in mortality rates was found."

    • Joydeck
      Joydeck Danrower

      Posted

      I have just listened to all 51 minutes of "Hardwired". The self-confidence of many a TED speaker is admirable.

      Having had an interest in such matters for decades, nothing much was new to me. Studies contradict on these matters and you sum it up well in saying, "...we are primitive in our knowledge."

  • Flutterbie57
    Flutterbie57 Danrower

    Posted

    I have not listened to your post yet, but I will. I found a very interesting article many years ago, written by a Doctor, at the time, when immunisation was first used. He warned that over immunising the body would scramble the immune system. He believed that any more than six or seven immunisations would have a negative effect on the body. Another possible cause ?

    ..I found that article 23 years ago when I got my first auto immune problem.... Fibromyalgia. My health deteriorated shortly after having one of the Hepatitis vaccines , and Fibro was then diagnosed...My second auto immune problem (Lichen Planus), came on a day after having an operation.(unofficial and off the record cause, made by a specialist, was that it was related to a fairly new drug I was given. ) My third auto immune problem , PMR, began to show signs after a stressful time and more travel injections

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