worse reflux since ppi increased.

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Increased my ppi 8 weeks ago. Reflux became much worse about 48 hours after increase. (I did have a pill stuck in my throats the week before). 

I'm wondering if the increase is just too much for me and following a  consultation yesterday I've decreased my dose back to what it was. 

My oesophagus was described as 'beautiful' by the practitioner, no evidence of the pill or oesophagitis. It's just so uncomfortable! 

 

1 like, 11 replies

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11 Replies

  • Posted

    Can u have uncomfy/ sore oesophagus even when no oesophagitis present?

    If so what would be causing it?

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    • Posted

      I've had the same for weeks. Convinced it was a side effect of increased disease of lansoprazole causing dry mouth and throat. Reduced dose this morning...different person this evening! Can't believe how bad it was. Will see GP asap to confirm specialist feedback and to see what to do next with regurgitation. I think my hiatus hernia has possibly got worse. 

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  • Posted

    Regarding the PPIs, you should be on a minimum effective dosage. 

    If this dosage works for you (increased) in comparrison to the previous, then you take it, if you think that the previous did the good job then lower it. Simple as that. Also try H2 at night if heartburn returns. I would suggest to practice a lower dosage of PPIs and combine withe H2 blockers to achieve the desired result.

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  • Posted

    It seems many on the forum think that taking a ppi will stop or reduce reflux which is not the case.The ppi meds only change the acidity level to less acidic - it has nothing to do with reflux control.
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    • Posted

      What are you trying to say here? They reduce reflux for some. Reflux is caused by gastritis as well, to be more general by stomach lining inflammation and H. Pylori sometimes and PPIs help here. 

      Regarding the reflux reflux, It won't be reduced but it will eliminate the acid and therefore the reflux wont be noticeable. This applies for classic GERD doesn't really apply for LPR unfortunately.

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    • Posted

      It actually reduces the amount of acid production so therefore the less acid produced the less refluxant to irritate. With less acid the chances of reflux are reduced. With less acid around tissue can start healing.

      It also depends what is being refluxed if the valves are to blame or other motility issues.

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    • Posted

      I absolutely understand how PPIs work. My concern is around the side effects of lansoprazole...as I see it. 

      Ive been on the lower dose now for almost a week and my energy levels have rocketed, still not back to normal though. 

      I am having some reflux and regurgitation, but not as bad as on the higher dose. Dry mouth has improved so much. 

      Im taking gaviscon advance as directed and seeing the GP next week. 

      I don't think I'm prepared for a change in medication as all PPIs have the same or similar side effects re dry mouth. 

      As I have a hiatus hernia of decent size, I will discuss referral to surgeon re nissen. My hernia is too large for Linx. 

      Never had any bother on the lower dose of lansoprazole, but I know HH can enlarge. 

      Ive done all the lifestyle changes, even blocks under the bed head, no alcohol, no chocolate, no tomatoes...BMI well within normal range.

      Its just pants! 

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    • Posted

      Fingers crossed u get the help needed to get relief.

      There are side effects on the meds I agree. I think i have some but without the meds i get worse.

      My journey continues. Consultant sending me for contrast CT and PH manometry. I been pretty ill for yr now. Endoscopy found not much.

      I need help as i never been longterm ill until i stopped smoki g 1 yr ago.

      It sucks.

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  • Posted

    There's a big difference in high and low stomach acid. There's also a big confusion among patients and doctors are quick to prescribe ppi drugs. Over 50 percent of people on ppi drugs actually do not have to be. Low stomach acid is usually the culprit in most cases and causes the same symptoms as high stomach acid. Your body must produce enough stomach acid to signal the valve to close, if not then reflux occurs. If you take ppi drugs and your reflux doesn't improve, you actually need to increase stomach acid and not reduce it to solve the problem. My doc. Gave me ppi for gastritis and kept me on them, I never at all had reflux. However now, my digestion has been severely altered by ppidrugs going on a year now even though I took myself off. They have caused severe harm for me when I should have only been on them for about three months. My stomach has never recovered from the reduced acid production caused by PPI. I now suffer from chronic constipation and gastroparesis after use of ppi drugs. My battle is to increase stomach acid to digest food and signal my valve to close. Good luck to everyone.

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