Worsening of depression/anxiety on increased dose.

Posted , 5 users are following.

I started Venlafaxine just over four weeks ago, on 75mg per day. The first week was rough, but after 8-9 days things improved. 9 days ago I increased the dose to 150mg per day - was fine for the first week but the last two days have been dreadful, really bad depression and anxiety. Part of the reason I know is because I've been diagnosed two days ago with COPD, and it's frightening me to death. I'd feel better if i could believe that part of the reason also is the increased dose, as at least I can think this will lift after a couple of weeks on it. Anyone any similar experiences to share, please?

0 likes, 7 replies

7 Replies

  • Posted

    Took 6 weeks for it to work at 150. I felt pretty rough until then but it does work so stick with it.
    • Posted

      Thanks Sarah - just coming up two weeks on 150mg so some time to go!
  • Posted

    Aw I know it's hard when you first start the medication. Side effect etc can be difficult to deal with.

    I would think your feeling this way because of the dramatic increase in your dosage. And your recent news. Give it time. You will start to feel the benefits soon but it does take time.

    For me between 6 and 10 weeks I started to feel much better.

    Don't rush yourself. Take it one day at a time and try some relaxation techniques. Anxiouty is awful, there are lots of tips on the Internet on how to relax your body. It's amazing house tense your body can get. Relaxing yourself will help you get through it.

    I hope this helps. Talking is a brilliant way to help also. 😆.

    • Posted

      Thanks Joanna,

      you're right, talking does help, and sharing experiences in these forums too. Easy to get things out of proportion when suffering anxiety and depression - doctor says more likely to die of a heart attack than COPD!

  • Posted

    Hi was wondering how you are now I have just had increase to 150 mg tuesday this week also doctor tapered me off mirtazapine which again ended Tuesday I have been on venlafaxine for nearly 6 weeks felt really ok Monday but each time I have increase I go downhill wondering when this will get better 


    • Posted

      Hi Dawn,

      Just over three weeks now on 150mg per day and still up and down like a roller coaster! Good days, bad days, no apparent rhyme or reason. I'll just tough it out, I guess.

  • Posted

    Thanks for replying guess it is a waiting game tough though take care we can do this x

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