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Xxifaxan and neomycin for small intestinal bacterial overgrowth

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helen18113
helen18113

I've been suffering with severe lower abdominal pain  and constipation for years but its been much worse over the past few months.    Ater numerous tests my GI ordered a lactulose breath test which was positive for methane. I'vw had two rounds of xifaxan both of which helped for a short time.  Then I followed the low Fodmap diet for 12 weeks During that time the pain and constipation returned.  My GI has now prescribed Xifaxan and neomycin.  I wondering if anyone here has used that combination.  If so were there side effects?  Did it help?  What was your dosage and for how long.  I am concerned about side effects because I have difficuty tolerating meds.  My GI said they are not absorbed and stay in the intestines so are usually well tolerated.  Thanks for listening.

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3 Replies

  • Lotsofpain
    Lotsofpain helen18113

    Posted

    J Clin Gastroenterol. 2010 Sep;44(8):547-50. doi: 10.1097/MCG.0b013e3181c64c90.A combination of rifaximin and neomycin is most effective in treating irritable bowel syndrome patients with methane on lactulose breath test.

  • Dancesame
    Dancesame helen18113

    Posted

    Helen,

    Where are you based?

    This combination has been tried various times, mainly in the states as I'm pretty sure, Rifaximin isnt available in the UK.

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