Zoledronic Acid advice

Was it a spontaneous fracture Paul or due to trauma?I can understand your anxiety and depression i too had compression fracture in May (t7),i am much older though so have been thrown on the scrap heap,you at your age should be offered all the possible help available and you should'nt be afraid to ask for it.

Hello, I'm not medically trained but I would say yes it does seem to be warranted. You're very young to have osteoporosis and now that you know you have Celiac and hopefully are going to be absorbing better on a gluten-free diet you have time to build your bones with nutrition and exercise but your osteoporosis is Advanced and the medication can help to slow down any bone loss over time. I'm assuming that they think your fractures are due to the osteoporosis. How about if you get a second opinion by another doctor or a naturopathic doctor to see if another viewpoint could lead you to a clear decision. Good luck to you. Also I read about Recent research into use of 3 milligrams of melatonin which yielded about 50% effectiveness of medications like Fosamax. Your doctors may not know of this given the research is a recent only within the last 4 years but if you Google it on Google Scholar or talk to a rheumatologist that has reviewed the research maybe they could educate you more.

Hello, I'm not medically trained but I would say yes it does seem to be warranted. You're very young to have osteoporosis and now that you know you have Celiac and hopefully are going to be absorbing better on a gluten-free diet you have time to build your bones with nutrition and exercise but your osteoporosis is Advanced and the medication can help to slow down any bone loss over time. I'm assuming that they think your fractures are due to the osteoporosis. How about if you get a second opinion by another doctor or a naturopathic doctor to see if another viewpoint could lead you to a clear decision. Good luck to you. Also I read about Recent research into use of 3 milligrams of melatonin which yielded about 50% effectiveness of medications like Fosamax. Your doctors may not know of this given the research is a recent only within the last 4 years but if you Google it on Google Scholar or talk to a rheumatologist that has reviewed the research maybe they could educate you more.

Yes, you are young to have this diagnosis.  Is it believed that your celiac disease is the culprit for bone thinning?  The underlying cause needs to be dealt with before any heavy duty drugs are administered, especially as you may have more than fifty years ahead of you and they can wreak a lot of havoc in that time.  My physiotherapist told me that sometimes the muscles along either side of the spine can get so tight, hard "like bricks" that they can cause vertebral fractures.  If you are stressed and worried this could be a real risk factor for you.

Please read up on the OP meds before committing to any of them.   You also need to know that the figures for "osteopenia" and osteoporosis were fairly arbitrarily set by the WHO some years ago.  These figures have been a boon to the pedlars of drugs. Some other things to think about - these did not exist as diseases in the past.  All humans lose bone density as they age, although I grant that you are young for this effect to have occurred.  We can help maintain and even improve our bone density through appropriate exercise and diet.  Supplements like calcium, D3, K2 (look up K2, not easy to get in modern diet but essential for proper calcium metabolism) magnesium and a few other things are important for bone health.  Weightbearing exercise is essential, can be as simple as a daily walk.  I guess your diet must be fairly strict, but please don't consume too much processed food and eliminate added sugar and sodas, diet or otherwise, from your life.

The major cause of fracture is falling, so the most effective thing to do is to learn how to maintain muscle strength and improve balance.  Exercise like tai chi is super for that.  None of the bone meds will give you stronger bones, although they may improve density reading on the machine.   

Thank you for all of you're responses, having performed some research weighted the pro's & Con's I have decided along with having two rhumatolagist advice (one being a second opinion) to go ahead with the infusion this coming Wednesday. 

Im worried of course but believe there's a risk greater in not having it.

Oh my good god.....had the infusion yesterday at 2pm fine all night and then this morning chest pain across the top every time my lungs get to around half capacity and then at 4pm today my thigh bones became painful.

Let's hope it's short lived 🙏🏻

Well the feared happened, I need support somebody with midical experiance to advise

I have today been diagnosed with ONJ osteonicrosis of the jaw, on 14th september i had IV zoledronic acid whereby I informed them I had just had preventitive wisdom teeth extractions (x3) on August 25th on the day of the rhumatology stating that I was to have IV zoledronic acid I still had severe swelling and bruising of the jaw and the meds were administered 3 weeks later

my question is all the data and studies etc point to ONJ can develope several years after IV zoledronic acid >4 years so how can it happen 4 weeks after and how would I go about reporting to someone as I cannot see any cases so close to administration????

any help welcome, I am gutted because I thought I was doing the right thing for bone recovery