Zyprexa, Zypexa withdrawl and depression

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Hi all,

I've been on Zyprexa for about a year and a half at 15mg. I was put on Zyprexa to help with severe treatment resistant depression. I also take 150mg of Effexor and 300mg of Welbutrin. In the past year my depression has slowly gotten worse and I suspect it's the Zyprexa. About 3 months ago I decided to taper myself off Zyprexa. I went from 15mg to 7.5mg for 3 months. I experience moderate sleeping issues (I sleep between 4-8 hours and wake up about 10 times during the night), nausea and a dramatic increase in depression. My highs are lower and my downs are longer and more severe.

My two questions are this: 1) Has anyone experienced increased depression as a result of taking Zyprexa

2) Has anyone experienced an increase in depression as a result of Zyprexa withdrawal.

Any replies are greatly appreciated.

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1 Reply

  • Posted

    HI Josh

    I am also tapering off zyprexa at present. I am tapering very slowly at 10% every two weeks. I was also put on it for depression but it has not,helped at all. i cant say my depression is worse but it certainly is no better.I am not sure how I will feel,when i am totally off.

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