Acute Coronary Syndrome research hub
13 indexed studies · 8 currently recruiting
- authorisedTherapeutic confirmatory (Phase III)
Triple oral therapy with bempedoic acid vs usual care in early lipid management of patients with acute coronary syndrome
This study looks at people who have recently had a heart attack or serious chest pain, known as acute coronary syndrome. Researchers want to see if adding a cholesterol medicine called bempedoic acid to standard daily pills helps lower bad cholesterol faster and more safely than usual NHS care alone.
Italy - recruitingPhase III and phase IV (Integrated)
RE-DUAL TICLO PCI: Dual Therapy with dabigatran/ticagrelor versus Dual Therapy with dabigatran/clopidogrel in ACS patients with indication for NOAC undergoing PCI.
This study looks at two different ways to combine medicines for people who have had a heart attack and need a procedure to unblock their heart arteries. It aims to find out which combination is safer in terms of causing less bleeding, while still preventing blood clots.
Netherlands - recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Randomized, Double-Blind, Placebo-controlled, Event-driven Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, After a Recent Acute Coronary Syndrome
This study is testing a new medicine called Milvexian for people who have recently had a heart attack or similar heart problem. We want to see if it can prevent future serious heart issues better than existing treatments, with fewer side effects.
Netherlands · Latvia · Denmark - authorisedTherapeutic use (Phase IV)
Combined impact of cardiovascular polypill treatment and a specific nurse education program on adherence to therapy in patients with ACS: a randomized study
This study looks at how well people with a recent heart problem take their medicines. It also checks if a special medicine (a 'polypill') and nurse support help them stick to their treatment. Researchers want to see if these things improve heart health.
Spain - recruiting
Biomarkers in Acute Cardiac Care
Researchers are studying new ways to diagnose heart attacks better and find out what causes chest pain. They're looking at different markers in the body and factors like lifestyle to improve how we understand and treat heart problems.
Germany - authorisedTherapeutic confirmatory (Phase III)
"MetCool ACS"- Metformin "Cooling" Effect on metformin-naive Patients Treated with PCI because of Acute Coronary Syndrome
This study looks at whether metformin, a common diabetes drug, can help patients who have had a heart attack and recently had a procedure to clear their blood vessels. Researchers want to see if it reduces the need for more heart-clearing procedures later on.
Poland - recruiting
Carotid Intraplaque Neovascularization Combined With Stress Echo
This study looks at a new way to predict heart attacks and strokes. It combines a standard heart stress test with a special neck ultrasound. This aims to find people at higher risk whose usual tests might miss them, by looking closely at fatty build-ups in blood vessels.
Canada - recruitingPHASE3
Aggressive Smoking Cessation Trial (ASAP)
This study looks at new ways to help people with heart conditions quit smoking. It compares combining a stop-smoking medicine with e-cigarettes against the medicine alone. The goal is to find the most effective and safest way to help you stop smoking for good.
Canada - recruiting
Myocardial Infarction Registry
This study looks at people who come to hospital with chest pains or signs of a heart problem. It helps doctors understand more about these conditions in real life, collecting information and blood samples to find better ways to diagnose and treat them.
Germany - recruiting
Barts Sex-CAD Database - Sex Hormones and Inflammatory Status in Coronary Artery Disease
This study looks at how hormones and inflammation affect heart artery disease in men and women, especially for women after menopause. Researchers at Barts Heart Centre hope to find better ways to treat heart conditions by understanding these differences.
United Kingdom - active not recruiting
Point of Care Evaluation of High-sensitivity Cardiac Troponin
This study is testing a new, rapid finger-prick test to help doctors quickly find out if someone arriving at the hospital with chest pain is having a heart attack. It aims to get results in about 10 minutes, much faster than current methods, helping patients get the right care sooner.
United Kingdom - recruiting
The Harefield Acute Myocardial Infarction Cohort
This study at Harefield Hospital collects blood and health information from patients having a heart attack. Researchers want to find new ways to understand and treat heart conditions by looking at inflammation and germs in blood samples.
United Kingdom - active not recruitingNA
LEADERS FREE II: BioFreedom™ Pivotal Study
This study is looking at a special stent called BioFreedom™ for people with heart problems who are at a higher risk of bleeding. It aims to see if this stent, with a short course of blood-thinning medicine, works as well as other common treatments.
United States · Canada · Denmark