Clinical research, explained in plain English.
Find clinical trials for your condition, understand what taking part involves, and decide whether a study might be right for you. Trusted, jargon-free information from Patient.info.
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Search all studies →A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
This study is testing a new, one-time eye injection for people with Geographic Atrophy (GA), a severe form of age-related macular degeneration (AMD). Researchers want to see if it's safe and helps improve or maintain vision. It involves a single treatment followed by long-term check-ups.
A Phase 3 Randomized, Double-blind, Multi-center Study of Adjuvant Nivolumab versus Placebo in Subjects with High Risk Invasive Urothelial Carcinoma
This study looks at a medicine called nivolumab for adults who have had surgery for high-risk bladder or urinary tract cancer. Researchers want to find out if taking this treatment after surgery helps stop the cancer from returning and helps people live longer compared with a dummy treatment.
AN OPEN-LABEL STUDY TO EVALUATE THE SAFETY AND PHARMACOKINETICS OF MIGALASTAT HCL IN SUBJECTS WITH FABRY DISEASE AND AMENABLE GLA VARIANTS AND SEVERE RENAL IMPAIRMENT OR END-STAGE RENAL DISEASE TREATED WITH HEMODIALYSIS
This study looks at a capsule medicine called Galafold (migalastat) for adults with Fabry disease who have severe kidney problems or are on dialysis. Researchers want to see how the body absorbs and clears the medicine, and check if it is safe and properly dosed for damaged kidneys.
Migraine and High Flow Oxygenotherapy at the Emergency Department (MiOx)
This study is testing whether breathing high-flow oxygen can quickly ease severe migraine pain in hospital emergency departments. Researchers are comparing pure oxygen with normal medical air to see if it reduces head pain within 30 minutes, helping patients feel better faster without needing as many strong painkillers.
Dupilumab step-down strategy to maintain remission in adult and adolescents patients with atopic dermatitis: a non-inferiority randomized trial
This study looks at whether adults with eczema that is well controlled by dupilumab can safely reduce their treatment. Researchers want to see if spacing out or lowering doses over one year keeps skin clear, reduces side effects, and cuts healthcare costs without eczema getting worse.
Long-term efficacy and tolerability of add-on pramipexole for anhedonic depression – an open label follow-up study
This clinical study investigates whether a medicine called pramipexole can help treat depression, especially when people find it difficult to feel pleasure or joy. Researchers want to see how well it works over time, how safe it is, and how it affects daily energy, sleep, and overall quality of life.
New to clinical research? Start here.
What is a clinical trial?
How research studies work and why they matter.
Understanding trial phases
Phase 1 through 4 explained in plain English.
What is a placebo?
Why some studies use a dummy treatment.
Understanding informed consent
What you'll be asked to agree to — and why.
How trial safety works
The checks that protect people taking part.
Can children take part in research?
How research with young people is regulated.