- active not recruitingNA
CHAMPION-AF Clinical Trial
This study compares a small heart device (WATCHMAN FLX) with standard blood-thinning medicines (such as DOACs) for people with an irregular heartbeat called atrial fibrillation. It aims to see if the device can prevent strokes just as well as the medicines.
United States · Australia · Belgium - active not recruiting
Preventing Recurrent Cardioembolic Stroke (The PRECISE Study)
This study aims to improve how we check for a heart condition called atrial fibrillation (AF) after a stroke. By finding better ways to identify who needs checking, we hope to prevent more second strokes for people in the UK.
United Kingdom - not yet recruitingNA
Telerehabilitation Decision Support System: Pilot Testing Protocol
This study tests a new online exercise system for people with conditions like stroke or long COVID. It uses special technology, including holograms, to help improve balance and movement from home. We want to see how well it works and if it's easy to use before a larger study.
Germany · Greece · Portugal - recruitingPHASE2, PHASE3
Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
This study is testing a new medicine, DM199, for people who have had a type of stroke called an ischaemic stroke. It aims to see if the medicine is safe and helps people recover better, especially those with fewer treatment options.
United States · Belgium · Canada - recruiting
Monitoring Arm Recovery After Stroke (MARS)
This study is testing a new phone app to help people recover arm movement after a stroke. It compares the app's accuracy to special lab cameras when measuring arm movements. The goal is to create a simple, affordable way to track recovery and improve treatments using video of everyday movements.
United Kingdom - recruiting
Neurofrailty: A Study of Late-onset Epilepsy and Its Associations
This study looks at adults who have their first seizure later in life. We want to see if there's a link between these seizures and conditions like stroke or memory problems (dementia) that might happen years later. We'll observe people's health over time to learn more.
United Kingdom - not yet recruitingNA
Piloting the Attention Training Technique for Post-Stroke Emotionalism
This study looks at a new technique called Attention Training (ATT) to help people who have had a stroke and experience uncontrollable crying or laughing (emotionalism). It aims to see if ATT can improve these symptoms and how it works.
United Kingdom - ongoing, recruitingTherapeutic exploratory (Phase II)
CONCISE COlchicine iN Circulating Inflammatory markers after StrokE
The CONCISE study is looking into whether a medicine called colchicine can help reduce swelling and inflammation in people after a stroke. Researchers want to see if it changes certain markers in the blood related to inflammation.
Ireland - active not recruitingNA
Physical Activity Maintenance Intervention for People With Stroke
This study aims to help people who have had a stroke stay active long-term. Many stroke survivors struggle to keep up physical activity after initial programmes. Researchers want to create a new programme with input from patients and staff to make it helpful and easy to stick with.
United Kingdom - recruiting
Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project
This study, called VESPAR, looks at how blood flow in the brain affects thinking problems like dementia, depression, and stroke. Researchers want to find better ways to measure brain blood flow and understand how it changes in different conditions to help plan future research.
United Kingdom - completed
Implementation of VR for upper limb rehabilitation after stroke (v1)
This study looks at a virtual reality (VR) system called NeuroVirt to help stroke survivors recover arm movement. It checks if it works well in the NHS, how much it costs, and if it encourages people to do their arm exercises to get better.
United Kingdom · England - recruiting
Safety and Efficacy of Aneurysms Treated With Endovascular Devices
This study looks at how safe and effective the newest devices are for treating brain aneurysms. Doctors want to see if these treatments work well and are safe for people with this condition, which can sometimes lead to a stroke or bleeding in the brain.
United Kingdom - enrolling by invitation
Co-designing a Stroke Rehabilitation Trial Toolkit
This study aims to create a 'toolkit' to help future stroke rehabilitation trials run smoothly. We're working with stroke survivors, families, and healthcare staff to design it. The goal is to make sure trials are effective, leading to better recovery for stroke survivors.
United Kingdom - recruitingNA
Awareness Detection and Communication in Disorders of Consciousness
This study explores how brain-computer technology can help people with severe conditions like disorders of consciousness or paralysis communicate. It aims to see if they can use their thoughts to answer yes/no questions, offering a new way to understand their awareness.
Ireland · United Kingdom - recruitingPHASE4
Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial Fibrillation Occurring Transiently With Stress
This study looks at whether blood-thinning medicines (anticoagulants) can prevent strokes and other heart-related problems in people who have had temporary episodes of an irregular heartbeat called atrial fibrillation (AF) during stressful times like surgery or serious illness.
United States · Argentina · Australia - recruitingNA
Feasibility of a Physiotherapy Programme, With Integrated telerehabIlitation to Increase Rehabilitation Time and Improve Motor Function
This study looks at a new way to help stroke survivors do more physiotherapy at home. It combines online exercises, goal setting, and self-help strategies. We want to see if this programme helps people recover better and reduce their disability after a stroke.
United Kingdom - not yet recruitingNA
EMG-Directed Virtual-Reality Training for Motor Stroke Rehabilitation
This study explores if special virtual reality training, using your muscle signals, can help people with stroke or spinal cord injury move their arms and hands better. It looks at how this training affects recovery and body changes.
United Kingdom - not yet recruitingNA
Virtual Reality in Occupational Therapy Upper Limb Stroke Rehabilitation
This study looks at using a virtual reality (VR) system called Resynk to help stroke survivors improve movement in their arm and hand. We want to see if it's practical and helpful for patients both in hospital and at home.
United Kingdom - recruitingPHASE2, PHASE3
Transcutaneous Spinal Cord Stimulation for Upper Extremity Function
This study explores a non-invasive treatment called transcutaneous spinal cord stimulation (tcSCS) for people with spinal cord injuries or stroke. It aims to improve arm and hand movement by gently stimulating the spinal cord through the skin. We want to understand the best ways to use this treatment and how it helps recovery.
Canada - recruitingNA
Virtual Reality and Field Training to Enhance Community Walking After Stroke
This study looks at whether using virtual reality and outdoor training can help stroke survivors walk better in their communities. It aims to improve walking skills and confidence using a four-week programme that combines special VR goggles and real-world practice.
Canada - recruitingNA
Biofeedback for Hemianopia Vision Rehabilitation
This study looks at a new training method called biofeedback for people who have lost half of their vision (hemianopia) due to brain injury like a stroke. It aims to see if this method helps improve eye movements and vision, and how best to use it.
Canada - recruiting
Changes in Sensitivity, Taste and Smell in Stroke Patients
This study looks at how stroke affects swallowing, taste, and smell. It gently checks swallowing with a small camera, measures sensitivity in the throat, and tests taste and smell. This helps us understand why some stroke patients have trouble eating and drinking.
Germany - not yet recruiting
High Risk of Death or Disability in Brain Hemorrhage: Role of Spot Sign and Secondary Markers
This study is looking at people who've had a brain bleed to see if certain signs on their brain scans can help predict their risk of death or long-term problems. It aims to improve how we identify patients who might need extra care.
France - recruitingNA
Evaluation of the Impact of the AVanCer Program Provided by the ARRPAC Day Center
This study looks at a new support program called AVanCer in Lyon, France, for adults who have had a stroke or brain injury. It aims to see how well the program helps people and their families, and if it could be used in other places.
France - recruitingNA
Assessment of an Intensive Motor Telerehabilitation Program for Stroke Patients
This study looks at a home-based exercise program using a special device for people recovering from a stroke. It aims to see if doing extra rehab at home can help improve movement and recovery, supervised remotely by a therapist.
France - active not recruiting
Anatomical and Functional Predictions of Blindsight Capabilities in Patients With Lateral Hemianopsia
This study looks at how your brain's structure and activity might explain why some people with vision loss after a stroke can still react to things they can't consciously see. It hopes to find better ways to understand and help manage this ‘blindsight’ phenomenon.
France - recruitingNA
Neurophysiological and Behavioral Study of the Cognitive Deficits Associated With Cerebral Small Vessel Disease in the SHIVA Cohort. SHIVA-CogNeurophys
This study looks at how a condition called Cerebral Small Vessel Disease (cSVD) affects thinking skills. We want to find new ways to spot these changes early using brainwave tests (EEG) and see if brain training or gentle electrical brain stimulation can help improve them.
France - not yet recruitingNA
Evaluation of the NEUROSWING Orthosis on Walking Speed in a Population With Dorsal and/or Plantar Flexor Deficits, With a View to a Reimbursement Application
This study looks at a new ankle support, the NEUROSWING orthosis, to see if it helps people with walking difficulties caused by conditions like stroke or MS. Researchers will compare it to a standard carbon ankle support to see if it improves walking speed.
France - recruiting
Evolution of Walking Abilities in Subacute Stroke Patients Hospitalized in Neurorehabilitation Center
This study looks at how walking improves in people recovering from a stroke. It follows stroke patients in rehabilitation centers for up to six months to see changes in their walking abilities. The aim is to better understand their recovery jouney.
France - recruitingNA
Neural Mechanisms of Music Intervention Chronic Arm Hemiparesis Following Stroke: A Single Case Series EEG Study
This study looks at how playing music might help people recover arm movement after a stroke. Researchers want to see if music therapy can reorganise the brain and improve arm function for stroke survivors. It involves home-based music sessions and brain wave measurements.
United Kingdom - active not recruiting
Systematic Assessment of Treatment Effectiveness for Long-Term Management of Stable Atrial Tachycardia in Inpatient and Outpatient Environments
This study looks at how well treatments work over a long time for people with a fast or irregular heartbeat called atrial tachycardia. Researchers want to see the long-term effects of these treatments on people's health, including their risk of stroke and even how long they live.
Germany - active not recruitingNA
Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion
This study compares a new device (Occlutech Flex II) for closing a small hole in the heart called a PFO, often linked to strokes, with existing standard devices. It checks if the new device is as safe and effective at closing the hole and preventing future strokes.
United States · Canada · Denmark - recruitingNA
Pilot Study: Home Use of Wearable Grasping Neuroprosthesis in Vascular Hemiparesis
This study looks at a special device called a Grasp Neuroprosthesis (GNP) that helps people who've had a stroke open and close their hand. It's already been tested in hospitals, and now researchers want to see how well it works when used at home for a whole year.
France - recruiting
The Origin and Role of Thromboembolism in the Pathogenesis of Ischaemic Stroke
This study looks at how blood clots cause strokes. We're using a special scan to find these clots and see where they come from. The aim is to better understand different types of stroke, especially when the cause isn't clear, to improve future treatments.
United Kingdom - recruiting
Prediction of Post-stroke Motor Recovery
This study looks at how well we can predict arm recovery after a stroke. It uses information like a patient's age and initial arm movement to guess how much their arm will improve three months later. This helps doctors plan the best care.
France - ongoing, recruitingHuman Pharmacology (Phase I)- Other
DMT in healthy subjects
This study is looking for healthy people over 18 to test a new medicine (DMT). It's an early-stage study to see how safe the medicine is and how it works in the body, not to treat a specific illness. It's an important first step towards understanding potential future treatments for conditions like stroke.
Netherlands - recruitingNA
MUSic Therapy In Complex Specialist Neurorehabilitation
This study looks at whether adding music therapy to standard rehabilitation helps people recover better after serious brain or spinal cord injuries. It compares music therapy to usual care to see if it improves daily activities and well-being in patients aged 16-80.
United Kingdom - recruitingPHASE3
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
This study looks at how best to prevent blood clots and bleeding in people who develop an irregular heartbeat (atrial fibrillation) after bypass surgery. It compares different common blood-thinning treatments.
United States · Brazil · Canada - not yet recruitingNA
Potential for Recovery of Voluntary Finger Extension After Stroke
This study looks at how some stroke survivors might regain finger movement, even years after their stroke. It tests a home exercise program with electrical stimulation to see who benefits and why.
United Kingdom - not yet recruitingNA
Volunteer Facilitated Discharge Assistance and Supports at Home (DASH) for People With Stroke
This study looks at whether a volunteer visiting stroke survivors at home can help them cope better. Researchers want to see if this support, alongside usual care, improves recovery for people who have recently left the hospital after a stroke.
Canada - not yet recruitingNA
Telerehabilitation of Balance Clinical and Economic Decision Support System
This study looks at a new way to help people with balance problems caused by stroke, memory issues, inner ear problems, or Long Covid. It uses a virtual coach at home to guide exercises and improve balance and well-being.
Germany · Greece · Portugal - recruitingNA
Somatosensory Stimulation for Unilateral Neglect Post Stroke (SSUN)
This study looks at a hands-on therapy called Mobilisation and Tactile Stimulation (MTS) for people who have had a stroke. It aims to see if MTS can help with 'neglect,' where people aren't aware of one side of their body, after at least 20 weeks post-stroke.
United Kingdom - recruitingNA
B2AD-Risk AFDAS Evolution of Burden of AF
This study looks at people who have had a stroke and then found out they have an irregular heartbeat called atrial fibrillation (AF). We want to understand how this AF changes over time to help improve treatments and prevention for future strokes.
Canada - recruiting
Falls in stroke survivors
This study looks at a new programme, called SAF, to help stroke survivors avoid falls after leaving hospital. It compares SAF with usual care to see if it reduces falls over 12 months. SAF involves a checklist and action plan to manage fall risks.
United Kingdom · England · Wales - active not recruitingNA
Amplatzer Amulet LAAO vs. NOAC
This study compares a device that closes off a small pouch in the heart (Amplatzer Amulet) with standard blood-thinning medicines (NOACs). It aims to see which is safer and better at preventing strokes in people with an irregular heartbeat called atrial fibrillation.
United States · Australia · Canada - active not recruiting
Electrical Impedance Tomography of Stroke and Brain Injury
This study is looking at a new, quick, and safe scanning method called Electrical Impedance Tomography (EIT) to image the brain after a stroke or head injury. We want to see if it can produce good images that match current scans like MRI or CT, potentially helping doctors give faster treatment.
United Kingdom - recruitingNA
Comparing Digitally and Traditionally Made Ankle Foot Orthoses
This study compares how two types of ankle-foot supports (AFOs) are made: the traditional plaster cast method and a new digital 3D printing method. We want to see if the digital AFOs work just as well for people with leg weakness, potentially making them faster and cheaper to produce.
Canada - active not recruitingNA
AMPLATZER PFO Occluder Post Approval Study
This study is looking at how well a small device, the AMPLATZER™ PFO Occluder, works to close a small hole in the heart (PFO) after someone has had a stroke. It's checking its safety and effectiveness in many patients across different hospitals.
United States · Canada · Germany - recruitingNot Specified
Spatial inattention grasping therapy for neglect post-stroke
This study looks at a new therapy, SIGHT, for people who've had a stroke and have spatial inattention. This condition makes it hard to notice things on one side. SIGHT uses special rods to help the brain relearn how to pay attention. We want to see if it helps and for whom.
United Kingdom · England - recruiting
Magnesium and Cognition After Stroke
This study looks into how magnesium levels might be linked to memory and thinking problems after a stroke. Researchers want to see if magnesium levels affect how well people recover their mental abilities after a stroke.
Germany