- recruitingPhase II
Randomised treatment of Acute Pancreatitis with Infliximab: Double-blind, placebo-controlled, multi-centre trial
This study tests whether a medicine called infliximab can help treat sudden, severe swelling of the pancreas (acute pancreatitis). Right now, there are no specific drugs to speed up recovery. Researchers want to see if giving this medicine quickly through a drip in hospital helps people get better sooner.
United Kingdom · England · Scotland - recruiting
How can we improve care for patients recovering from acute pancreatitis following discharge from hospital?
The PANORAMA study aims to improve care for people recovering from acute pancreatitis after leaving hospital. Researchers want to hear from patients, carers, and NHS staff through surveys, interviews, and questionnaires to discover what support is needed to help people stay well at home and avoid returning to hospital.
United Kingdom · England · Scotland - recruitingTherapeutic use (Phase IV)
Normal saline versus lactated Ringer’s solution for acute pancreatitis resuscitation, an open-label multicenter randomized controlled trial: the WATERLAND trial
This study, called WATERLAND, is comparing two common fluid treatments, normal saline and lactated Ringer's solution, for people with sudden inflammation of the pancreas (acute pancreatitis). Researchers want to see which fluid best prevents serious complications in the first month after treatment starts.
Spain · France - recruiting
Study's Care of Acute Pancreatitis at Saint-Etienne University Hospital.
This study looks at how well adults with acute pancreatitis are cared for in general medical wards compared to specialist digestive health wards at Saint-Etienne University Hospital. It simply collects information from patient records to help improve care.
France - recruitingPHASE2
Randomised Treatment of Acute Pancreatitis With Infliximab: Double-blind, Placebo-controlled, Multi-centre Trial (RAPID-I)
This study is looking at whether a drug called infliximab can help treat acute pancreatitis (a sudden inflammation of the pancreas). We want to see if it's safe and effective in reducing the impact of this serious condition. Participants will receive either infliximab or a dummy drug.
United Kingdom - not yet recruitingNA
Safety, Tolerability and Performance of the NucleoCapture Extracorporeal Therapeutic Apheresis Device in the Reduction of Circulating cfDNA/NETs in Subjects With Pancreatitis
This study looks at a new device called NucleoCapture for people with severe pancreatitis. It aims to see if this device is safe and can reduce harmful substances in the blood to help patients recover better. It compares those using the device with those receiving standard care.
United Kingdom - enrolling by invitationNA
Conventional Endoscopic Techniques Versus EndoRotor® System for Necrosectomy of Walled of Necrosis
This study compares a new device, the EndoRotor, with standard methods for clearing infected fluid collections in the pancreas. It aims to find out if the new device is better for treating a condition called 'walled off necrosis' in people with severe pancreatitis.
United States · Denmark · Germany - authorisedTherapeutic use (Phase IV)
Normal saline versus lactated Ringer’s solution for fluid administration in acute pancreatitis, an open-label multicenter randomized controlled trial: the WATERLAND trial
This study, called WATERLAND, is looking at which fluid drip is better for people with acute pancreatitis. It compares two common fluid types to see if one helps more by causing fewer serious problems or side effects.
Hungary