Acute Respiratory Distress Syndrome - ARDS research hub
10 indexed studies · 6 currently recruiting
- recruitingHuman Pharmacology (Phase I)- First administration to humans
MESENCHYMAL STROMAL CELL THERAPY FOR THE TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME - Validation of Mechanistic Pathways and Clinical Efficacy
This study is looking at a new treatment called 'mesenchymal stromal cell therapy' for a serious lung condition called Acute Respiratory Distress Syndrome (ARDS). It's an early-stage study to see if this new treatment is safe and how it works in people.
Sweden - recruitingTherapeutic confirmatory (Phase III)
Randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy of intravenous metoprolol in patients with Acute Respiratory Distress Syndrome (ARDS).
This study is testing if a heart medicine called metoprolol, given through a drip, can help people with severe lung problems (ARDS) get better faster. It's comparing metoprolol to a dummy treatment (placebo) to see if it helps patients breathe on their own sooner.
Spain - recruitingTherapeutic exploratory (Phase II)
Potential of FX06 to improve disease severity in Acute Respiratory Distress Syndrome patients (Ixion 2.0)
This study, called Ixion 2.0, is investigating a new treatment called FX06 for a severe lung condition called Acute Respiratory Distress Syndrome (ARDS). It aims to see if FX06 helps patients breathe on their own sooner compared to a dummy treatment.
Spain · France · Romania - recruiting
A study to see whether the lungs of very sick patients on an artificial lung machine heal more quickly with slower, deeper breathing
This study looks at how different breathing settings on a ventilator help very unwell patients with severe lung problems (ARDS) while they are supported by a special machine called ECMO. We want to see if letting the lungs rest more helps them heal faster.
United Kingdom · England · Scotland - not yet recruiting
Right Heart Injury Monitoring on ECMO
This study looks at how we can better monitor the right side of the heart in very sick patients on a special life support machine called VV-ECMO. This machine helps their lungs recover. We want to see if regular heart scans and blood tests can give us important information about their heart health during this critical time.
United Kingdom - authorisedTherapeutic confirmatory (Phase III)
PIrfenidone to prevent fibrOsis in ARDS. A RaNdomizEd controllEd tRial - PIONEER
This study, called PIONEER, is testing a medicine called Pirfenidone to see if it helps people with a serious lung condition called ARDS. Researchers want to know if it helps people breathe on their own sooner and stay out of intensive care, compared to a dummy pill.
Italy - recruiting
Study of the Immunological Pathophysiological Mechanisms Associated With Acute Respiratory Distress Syndrome
This study aims to better understand why some people with severe breathing problems (ARDS) react differently to treatments. Researchers will look at blood and lung samples to identify different types of ARDS. This could help develop new, more effective treatments.
France - active not recruiting
Clinical Evaluation of a Point of Care (POC) Assay to Identify Phenotypes in the Acute Respiratory Distress Syndrome
This study looks at a new test to help doctors understand a severe lung condition called ARDS. We want to see if this test can quickly identify different types of ARDS to help us predict how patients might recover and find better ways to treat them.
Ireland · United Kingdom - authorisedTherapeutic exploratory (Phase II)
Efficacy and safety of anakinra in non-COVID-19 related ARDS. ESKA study.
This study is looking at a medicine called Kineret to treat a serious lung condition called ARDS in adults. We want to see if Kineret can help patients breathe on their own sooner, without needing a ventilator.
Italy - active not recruitingNA
A Trial of Staff Time With Proned Patients in the ICU Using the 'BathMat'
This study looks at a new cushion, called 'BathMat', to help very sick patients in intensive care breathe better by lying on their front. It aims to make it easier and safer for staff to move patients and prevent skin problems, often saving time too.
United Kingdom