- authorisedHuman Pharmacology (Phase I)- Bioequivalence Study
A double blinded, balanced, randomized, two-treatment, two-period, two-sequence, single dose, crossover, bioequivalence study comparing Lisdexamfetamine Dimesylate capsules 10 mg, manufactured by Ohm Laboratories Inc. (A Sun Pharma Company), 14 Terminal Road, New Brunswick, 08901, NJ, USA with Vyvanse (Lisdexamfetamine Dimesylate) 10 mg capsules; Product of Takeda Canada Inc., Toronto Ontario ON M5H 4E3, Canada, in healthy adult, human subjects under fasting condition.
This study is comparing a new version of ADHD medication (Lisdexamfetamine Dimesylate) with the existing Vyvanse. Researchers want to check if both versions work the same way in healthy adults. It's a single dose test to ensure they are equally effective.
Romania - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
An open label, balanced, randomized, two-treatment, two-period, two-sequence, single-dose, crossover, bioequivalence study comparing Lisdexamfetamine Dimesylate capsules 70 mg, manufactured by Sun Pharmaceutical Industries Limited, India with Elvanse (lisdexamfetamine dimesylate) 70 mg hard capsules, Marketing Authorization Holder: Takeda Pharmaceuticals International AG Ireland Branch, Block 2, Miesian Plaza, 50-58 Baggot Street Lower, Dublin 2, D02 HW68, Ireland, in healthy adult, human subjects under fasting condition.
This study compares a new version of ADHD medication (like Elvanse) with the original one. We want to see if they work the same way in healthy adults. This helps ensure new medicines are just as good as existing ones for people with ADHD.
Romania - recruiting
Investigating the Impacts of Early Life Experience on the Brain & Behaviour
This study explores how early life experiences can affect your brain, behaviour, and immune system as an adult. We want to understand why some early experiences lead to mental health challenges later on, helping us identify and support young people who might need help in the future.
United Kingdom - enrolling by invitationNA
DBT Skills Group for Adolescents with ADHD
This study looks at a special group therapy called DBT for teenagers aged 13-16 with ADHD. It aims to help them manage their feelings and improve social skills. The goal is to see if this group is helpful and practical for them.
United Kingdom - recruitingNA
Intensive-neurofeedback Protocol for Children With ADHD: A Proof-of-concept Study Comparing iAPF-personalized and Standard Theta-beta-ratio Training
This study looks at a special brain training called neurofeedback for children with ADHD. It compares a standard method with a new, personalised one to see if it helps reduce ADHD symptoms like inattention and hyperactivity, during fun holiday camps.
Germany - recruiting
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
This study, called BLOOM, looks at how young people's mental health develops between ages 9 and 25. It aims to understand early signs of mental health conditions like depression and ADHD, to help find ways to support young people before problems become serious.
Canada - recruiting
Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome
This study looks at how a diabetes medicine, sulphonylurea, affects brain development in children and adults with a specific genetic condition called iDEND syndrome. We want to see if starting this medicine early in life leads to better developmental outcomes.
United States · Italy · Norway - recruiting
Investigating Health, Equity, and Resilience in Girls and Women With ADHD Across the Lifespan
This study looks at how ADHD affects the health and well-being of girls and women in Canada, from childhood to older age. Researchers want to understand their life experiences, including hormones, development, and social factors, to gather important information about living with ADHD.
Canada - recruitingNA
Cognitive Remediation in Forensic Mental Health Care
This study looks at a special kind of mental exercise called 'cognitive remediation' for people in forensic mental health care. It aims to see if these exercises can improve thinking skills, everyday abilities, and mental well-being in patients dealing with conditions like schizophrenia or ADHD.
Canada - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
An open label, balanced, randomized, two-treatment, two-period, two-sequence, single-dose, crossover, bioequivalence study comparing Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate and Amphetamine Sulfate Tablets (Mixed Salts of Single Entity Amphetamine Product) 30 mg, manufactured by Frontida Biopharm. Inc., Philadelphia, USA with Attent 30 mg (Mixed Amphetamine Salts tablets) manufactured by Teva Israel Ltd., in healthy adult, human subjects under fasting condition.
This study compares a new 30mg ADHD medication with an existing one to ensure they work the same way in healthy adults. It's a quick, one-dose test to check if the body handles both medicines similarly, helping ensure new versions are just as effective.
Romania - recruitingPHASE4
AWARE: Management of ADHD in Autism Spectrum Disorder
The AWARE study is testing different ADHD medicines in children and teenagers (aged 4-17) who also have autism. It aims to find out which medicines work best and how to best manage ADHD symptoms for them, as current guidance is limited.
United States · Canada