Alzheimer Disease, Early Onset research hub
6 indexed studies · 4 currently recruiting
- active not recruitingPHASE1
A Study to Assess THN391 in Subjects With Alzheimer's Disease
This study is for people aged 65-85 with early Alzheimer's and small vessel disease. It tests a new drug, THN391, or a dummy drug, over 6 months to see if it's safe and how it behaves in the body. It involves clinic visits, scans, and memory tests.
Netherlands · United Kingdom - recruitingPHASE1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL628 in Participants With Early Alzheimer's Disease
This study is testing a new drug, DNL628, for people with early Alzheimer's disease. Researchers want to see if it's safe, how the body handles it, and if it has any effects. Participants will receive either the drug or a placebo.
Netherlands · United Kingdom - recruitingPHASE1, PHASE2
Study of ARO-MAPT-SC in Healthy Subjects and Subjects With Early Alzheimer's Disease
This study is looking at a new treatment called ARO-MAPT-SC for early Alzheimer's disease. Researchers want to see if it's safe, how the body handles it, and if it could help people with this condition.
Canada · New Zealand - recruitingPHASE3
Donepezil Versus Non-drug Treatment in Alzheimer's Disease.
This study compares two ways to help people with Alzheimer's disease: a drug called donepezil versus support like memory and thinking exercises. It wants to see which approach works better for people living with Alzheimer's symptoms after six months.
France - active not recruitingPHASE2
Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease
This study is looking into a new medication called BMS-986446 for people in the early stages of Alzheimer's disease. Researchers want to see if it helps with memory and thinking, if it's safe to use, and if people can take it without too many problems. It's a new treatment being tested.
United States · Australia · Belgium - recruitingNA
Network-based biOmarker Discovery of Neurodegenerative Diseases Using Multimodal Connectivity
This study aims to find new, simple ways to spot early signs of Alzheimer's and Parkinson's diseases. Researchers will use special brain scans to look at how different parts of the brain connect, hoping to find unique patterns that point to these conditions sooner.
France