Aortic Valve Calcification, Inflammation, Calcification, Aortic Valve Disease, Cardiovascular Diseases, Aortic Valve Stenosis research hub

Does Colchicine Reduce Progression of Aortic Valve Stenosis? Colchicine and Inflammation in Aortic Stenosis (CHIANTI): A placebo-controlled, double-blind, multicenter randomized trial.

This study looks at whether a widely used medicine called colchicine can slow down the hardening of the heart's aortic valve. Researchers will compare people taking colchicine with those taking a dummy pill, to see if it helps keep the valve working better for longer. It's a big study to find out if this treatment could be useful.