Autism spectrum disorder research hub
28 indexed studies · 24 currently recruiting
- authorisedTherapeutic exploratory (Phase II)
Effect of faecal microbiota transplant on the expression of autism spectrum disorder core symptoms in children – open-label phase II clinical trial (FMT-PAS)
This study is exploring if a special treatment called a faecal microbiota transplant (FMT) can help reduce some core symptoms of autism in children. It's a Phase II trial, meaning it's still an early stage of testing to see how well it works and if it's safe.
Czechia - active not recruitingPHASE2
Proof of Concept Study on Pitolisant Effect on Autism Spectrum Disorders in Children and Adolescents
This study is looking into a new medication called Pitolisant for boys aged 6 to 17 with Autism Spectrum Disorder (ASD). It aims to see if Pitolisant helps manage ASD symptoms and if it's safe to use, compared to a dummy pill.
France · Italy · Spain - authorisedTherapeutic exploratory (Phase II)
A randomized, placebo-controlled, double-blind, 2-period cross-over study in youth with autism spectrum disorders evaluating social and repetitive behaviors after four weeks of twice daily-doses of 24IU of intranasally administered oxytocin
This study looks at how a nose spray with a substance called oxytocin might affect social skills and repetitive behaviours in young people with autism over four weeks. We want to see if it makes a difference.
Norway - recruiting
A Game-based Neurodevelopmental Assessment for Young Children
This study is testing a new tablet game for children aged 3-8 years to help quickly and accurately spot developmental differences like ADHD or autism. It compares the game's results with other assessments to see if it's a reliable new tool.
United Kingdom - recruiting
Brain Imaging in Babies Study
This study looks at how babies' brains develop from before birth until they are 3-4 years old. Researchers use safe brain scans and check children's behaviour to understand brain growth. They also want to see if they can predict conditions like autism and ADHD early on, and how COVID-19 might affect brain development.
United Kingdom - recruitingNA
Investigating the Clinical Utility of the Oxford Virtual Autism Assessment Tool (OVAAT)
This study is testing a new online tool, the Oxford Virtual Autism Assessment Tool (OVAAT), to see how well it can spot signs of autism in young people aged 13-18. Researchers want to know if it's as good as or better than existing assessments.
United Kingdom - enrolling by invitation
Complementary & Integrative Healthcare for Children With Autism: A Pilot Study
This study looks at how online tools can help assess complementary therapies for children with autism. It aims to see if these therapies might improve symptoms and if a larger study would be possible. Children aged 3-12 with certain autism symptoms might be able to take part.
United Kingdom - not yet recruiting
Environmental Influence on Mental Illness Via Modifications of Genomes and Metabolomes in Adolescents With Autism
This study looks at how the environment affects mental health in autistic teenagers. Researchers want to understand why some autistic young people develop mental health conditions and how to offer them more personalized support. They will study genes and body chemicals to find clues.
Ireland · Romania · United Kingdom - not yet recruiting
Assessment of the Usability/acceptability of the Little Journey App by Parents/guardians/legal Representatives and Children Aged Between 3-12 Years Old Who Have a Diagnosis of Autism Spectrum Disorder (ASD).
This study is looking at how easy and helpful a special app called 'Little Journey' is for children aged 3-12 with autism. It wants to see if the app can make hospital visits less scary for them and their families.
United Kingdom - not yet recruitingNA
CFT Guided Self-help Intervention: Parents of Autistic Children
This study is testing a new self-help program for parents of autistic children aged 6-17. It uses compassion-focused techniques to help parents manage stress and improve their well-being. It's guided and involves workbooks and audio.
United Kingdom - recruitingNA
Caregiver Training to Support Children With Social Communication Challenges
This study looks at a special programme called 'More Than Words' for parents of young children with communication challenges, including those with autism. It aims to see how well it works, especially when delivered online, and how best to study it further.
Canada - not yet recruitingNA
Duration of Moment in Autism
This study looks at how children with autism see and pay attention to things, compared to other children. We want to see if children with autism process information faster. This might help us understand their experiences with sensory information and social situations.
France - recruitingNA
REward SYSTem in Autism Spectrum Disorder and Addictive Disorder
This study looks at how the brain's 'reward system' works in people with autism and those with food addiction, compared to healthy volunteers. We use special brain scans (MRI and EEG) to understand more about these conditions and how they might be linked in the brain.
France - active not recruitingNA
Purrble's Soothing Touch for Eating Disorders and Autism
This study looks at how a cuddly device called Purrble might help people on the waiting list for eating disorder treatment. It aims to see if Purrble can help with managing emotions, sensory feelings, and anxiety while they wait to start therapy.
United Kingdom - recruiting
Psychometric Validation of the Camouflaging Autistic Traits Questionnaire
This study looks at a new questionnaire called CAT-Q to understand how autistic teenagers in Germany try to fit in by hiding their traits. It wants to make sure the questionnaire works well in German to help with diagnosis and support for young people aged 13-21.
Germany - recruitingNA
Adaptation of the NEAR Cognitive Remediation Method to Child and Adult Autism by Including Social Scenarios and Skills
This study looks at a new way to help teenagers and adults with autism improve their thinking skills and social understanding. It adapts an existing method by adding social scenarios to help with daily interactions.
France - recruiting
Parenting with an Autism Spectrum Disorder
This study looks at the lives of parents with autism to understand their experiences and mental health. It also checks if a special parenting program could help them. We want to find out what support autistic parents need.
Germany - recruitingNA
EEG Microstates Across At-Risk Mental States
This study looks at brain activity in young people (15-30) with or at risk of certain mental health conditions like depression, psychosis, and autism. It uses special scans and tests to understand how brain patterns might be linked to these conditions and overall well-being.
France - not yet recruitingPHASE2
Use of Low Doses of Interleukin-2 in Autism Spectrum Disorders
This study is looking at a new treatment called ILT-101 for children aged 6 to 8 with autism. It aims to see if a low dose of this medicine can help improve autism symptoms by balancing certain immune cells, especially in children whose mothers had immune issues during pregnancy.
France - recruiting
Genetic of Intellectual Deficiency and Autism Spectrum Disorders (RaDiCo-GenIDA)
This study aims to create an online database about intellectual disabilities and autism linked to known genetic changes. Families will share information through questionnaires to help doctors better understand these conditions and provide more personalised care.
France - enrolling by invitationPHASE2
ML-004 Open-Label Extension Study in Adults and Adolescents With Autism Spectrum Disorders (ASD)
This study is looking at a new tablet treatment, ML-004, for autism in young people and adults. It's a follow-up study for those who have already completed a previous trial, focusing on how safe the medication is over time.
United States · Australia · Canada - recruiting
Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome
This study looks at how a diabetes medicine, sulphonylurea, affects brain development in children and adults with a specific genetic condition called iDEND syndrome. We want to see if starting this medicine early in life leads to better developmental outcomes.
United States · Italy · Norway - not yet recruitingPHASE2
Open Label Phase IIa Trial Evaluating the Effect and Safety of Transplantation of Fecal Microbiota in Children With Autism Spectrum Disorders and Gastrointestinal Symptoms
This study looks at whether a treatment called Faecal Microbiota Transplantation (FMT) can help children aged 3 to 6 with autism and gut problems. It explores if changing gut bacteria can improve tummy issues and social communication.
France - recruitingNA
Understanding the Mechanisms of Autism : an MRI and Social Cognition Study
This study uses brain scans and eye-tracking to understand how autism affects the brain and social skills. We're looking at children and young people with autism and those without. The goal is to find better ways to understand and monitor autism.
France - recruitingNA
Characterization of Social Cognition Profiles in Children and Adolescents With Neurodevelopmental Disorders: a Clinical Study Using a Multidimensional Battery
This study looks at how children and teenagers (8-16) with conditions like ADHD or autism understand social situations. Researchers are using new tests to better understand their social skills. The aim is to help create better support for them in the future.
France - recruitingPHASE2
Home-based Transcranial Direct Current Stimulation (tDCS) to Promote Social Communication and Behaviour in Children With Autism Spectrum Disorder (ASD)
This study looks at whether a gentle brain stimulation, called tDCS, given at home, can help young people aged 9-18 with autism. We want to see if it improves their social skills and helps them manage their feelings and behaviours better.
Canada - recruitingNA
Impact of Equine-Assisted Therapy on the Quality of Life of Children with Autism Spectrum Disorders (ASD)
This study looks at how horse-assisted therapy might improve the lives of children aged 8-12 with autism and their families. It’s a small first step to see if this type of therapy can help with communication, social skills, and overall well-being.
France - recruitingPHASE4
AWARE: Management of ADHD in Autism Spectrum Disorder
The AWARE study is testing different ADHD medicines in children and teenagers (aged 4-17) who also have autism. It aims to find out which medicines work best and how to best manage ADHD symptoms for them, as current guidance is limited.
United States · Canada