Autosomal Dominant Polycystic Kidney Disease research hub
6 indexed studies · 3 currently recruiting
- authorisedHuman Pharmacology (Phase I)- First administration to humans
A First-in-Human Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of MR-L45 in Healthy Adults
This early-stage study is looking at a new medicine called MR-L45. It's being given to healthy adults for the first time to see if it's safe, how well people tolerate it, and how it moves through the body. This research could eventually help people with a kidney condition called Autosomal Dominant Polycystic Kidney Disease.
Netherlands - ongoing, recruitingTherapeutic use (Phase IV)
Treatment of vascular stiffness in patients with autosomal dominant polycystic kidney disease
This study is looking at ways to improve blood vessel health in people with Polycystic Kidney Disease (ADPKD). It compares a high-salt diet to a potato starch placebo and tests a common medication called amiloride to see how it affects blood vessel stiffness.
Netherlands - active not recruitingNA
Renal Denervation in ADPKD- RDN-ADPKD Study
This study looks at a procedure called renal denervation (RDN) to help manage high blood pressure in people with Polycystic Kidney Disease (ADPKD). It aims to see if RDN is safe and helps lower blood pressure, which could protect their kidneys.
Germany - recruitingPHASE1
Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease
This study is looking at a new medicine called AZD1613 for adults with Polycystic Kidney Disease (ADPKD). It aims to check its safety, how well the body handles it, and if there are any side effects.
United States · China · United Kingdom - recruitingPHASE3
Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)
This study looks at whether metformin, a common diabetes drug, can help slow down kidney disease in people with Polycystic Kidney Disease (ADPKD). The goal is to improve health and quality of life for those affected.
Australia · New Zealand · United Kingdom - recruiting
National Registry of Rare Kidney Diseases
This registry is collecting information from people with rare kidney diseases across the UK. It aims to improve understanding, create better care guidelines, and help develop new treatments for these conditions. If you have a rare kidney disease, your information could help.
United Kingdom