Autosomal Dominant Polycystic Kidney Disease (ADPKD research hub
4 indexed studies · 2 currently recruiting
- recruiting
Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease
This study looks at blood pressure in young people aged 12-17 who are at risk of ADPKD, a kidney condition. It uses MRI and genetic tests to understand how common high blood pressure is in this group, hoping to improve early care.
United Kingdom - active not recruiting
Polycystic Kidney Disease 1 (PKD1) Gene Variant Groups in Autosomal Dominant Polycystic Kidney Disease
This study aims to understand the different genetic types of Autosomal Dominant Polycystic Kidney Disease (ADPKD) in people. Researchers want to see how these genetic differences affect the disease and who gets it.
United States · Belgium · Canada - recruitingPhase III
Implementation of Metformin theraPy to Ease DEcline of kidney function in Polycystic Kidney Disease (IMPEDE-PKD): randomised placebo-controlled trial
This study looks at metformin, a common diabetes drug, to see if it can slow kidney disease in people with ADPKD. It's for adults aged 18-70 and involves taking tablets daily for two years to understand if it helps protect kidneys.
United Kingdom · England · Northern Ireland - recruitingPHASE2
Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW)
This study, called AGLOW, is looking at a new medicine called VX-407 for a kidney condition called Autosomal Dominant Polycystic Kidney Disease (ADPKD). It aims to see how it affects kidney size, if it's safe, and how the body handles it in specific patients with certain genetic markers.
United States · Belgium · Canada