Axial Spondyloarthritis research hub
17 indexed studies · 14 currently recruiting
- recruitingTherapeutic confirmatory (Phase III)
A Multicenter, Open-Label Extension Study to Assess the Long-Term Safety, Tolerability, and Efficacy of Bimekizumab in the Treatment of Study Participants with Active Axial Spondyloarthritis, Ankylosing Spondylitis, and Nonradiographic Axial Spondyloarthritis
This study looks at the long-term safety and how well a medicine called bimekizumab works for people with axial spondyloarthritis. It helps us understand its effects over a longer period.
Hungary · Poland · France - recruitingTherapeutic exploratory (Phase II)
A Phase 2 open-label imaging study to explore the effects of sonelokimab in patients with active axial spondyloarthritis
This study is looking at a new medicine called sonelokimab for people with a type of arthritis affecting the spine, called axial spondyloarthritis. It aims to see how the medicine might reduce inflammation in the back and hips over 12 weeks, using special scans.
Germany - recruitingNot Applicable
Using everyday devices to measure axial spondyloarthritis
This study looks at whether everyday gadgets, like smartphones, smartwatches, and wireless earphones, can track how well people with axial spondyloarthritis move. Researchers want to see if these devices can accurately measure spinal stiffness, potentially helping people check their condition from the comfort of their own homes in the future.
United Kingdom · England - recruiting
Improving the diagnosis and referral of patients with axial spondyloarthritis into specialist care
Axial spondyloarthritis (axSpA) is a painful inflammatory condition affecting the spine. Getting a diagnosis currently takes up to eight years. This UK study is testing a new tool to help GPs spot axSpA much sooner. Participants aged 16 to 50 receive expert hospital checks, scans, and blood tests.
United Kingdom · England - recruitingTherapeutic use (Phase IV)
Tofacitinib in early active axial spondyloarthritis: a prospective, randomized, double-blind, placebo-controlled multicentre study - FASTLANE
This study, called FASTLANE, is looking at a medicine called tofacitinib for early active ankylosing spondylitis. Researchers want to see if it helps reduce disease activity and symptoms. It compares tofacitinib with a dummy pill and a common painkiller.
Germany · Bulgaria · Poland - recruitingTherapeutic confirmatory (Phase III)
A Phase 3 Randomized, Placebo-Controlled, Double-Blind Program to Evaluate Efficacy and Safety of Upadacitinib in Adult Subjects with Axial Spondyloarthritis Followed by a Remission-Withdrawal Period
This study is testing a new medicine, Upadacitinib, for adults with a type of arthritis called axial spondyloarthritis. It's comparing the medicine to a dummy pill to see if it helps reduce pain and stiffness, and if it's safe to use.
Germany · France · Bulgaria - recruitingTherapeutic use (Phase IV)
Rapid pain control in Ixekizumab targeted axial spondyloarthritis
This study looks at how quickly a medicine called Taltz (ixekizumab) helps control pain in people with a type of arthritis called axial spondyloarthritis. Researchers are using special brain scans to see changes in pain signals very early in treatment.
Germany - active not recruitingPHASE3
A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Subjects With Active Axial Spondyloarthritis Including Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis
This study looks at a medicine called Bimekizumab for long-term safety and how well it works in people with a type of arthritis affecting the spine, including Ankylosing Spondylitis. It's for people who have already been in related Bimekizumab studies.
United States · Belgium · Bulgaria - recruitingPHASE1
A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults
This study is looking at how a medicine called bimekizumab works in the body when given in different ways. It's for adults with psoriatic arthritis or a type of back pain called axial spondyloarthritis. We want to see if different ways of giving the medicine are equally safe and move through the body similarly.
United States · Bulgaria · Czechia - recruitingPHASE4
ToFAcitinib in Early Active Axial SpondyloarThritis:
This study is testing a medicine called tofacitinib for people with early, active axial spondyloarthritis. It aims to see if tofacitinib works better than a dummy pill (placebo) at reducing symptoms and is safe to use. Patients will also take their usual anti-inflammatory medicine.
Germany - recruiting
British Axial Spondyloarthritis Inception Cohort
This study looks at how a condition called axial spondyloarthritis (axSpA) affects people in the UK. We want to understand how quickly people are diagnosed, how their health changes over time, and the impact it has on their lives and work.
United Kingdom - recruiting
A LONGITUDINAL OBSERVATIONAL STUDY to EVALUATE the EFFICACY of MOVEMENT and IMPLEMENT CONCRETE MOVEMENT RECOMMENDATIONS with the HELP of MOBILITY TRACKING with SMARTWATCHES in SUBJECTS with AXIAL SPONDYLOARTHRITIS
This study uses smartwatches to track activity in people with a type of arthritis called axial spondyloarthritis. The aim is to understand how exercise helps manage the condition and to create clear, useful exercise advice to improve daily life and reduce flare-ups.
Germany - active not recruitingPHASE3
A Study Evaluating the Effect of Filgotinib in Participants With Active Axial Spondyloarthritis
This study is looking at a new medication, filgotinib, for people with active axial spondyloarthritis (axSpA). We want to see if it helps reduce symptoms and is safe, comparing different doses to a dummy pill.
Belgium · Bulgaria · Czechia - not yet recruitingNA
Efficacy of Non-invasive Vagus Nerve Stimulation for Axial Spondyloarthritis Resistant to Biotherapies
This study looks at whether a gentle electrical stimulation of a nerve in the ear, called Vagus Nerve Stimulation (VNS), can help people with a type of arthritis called axial spondyloarthritis that hasn't improved with other strong medicines.
France - recruitingNA
axSEND: Exploring Immune and Microbiota Effects of a Partial Enteral Nutrition Diet in Axial Spondyloarthritis
This study looks into how a special liquid and food diet (Partial Enteral Nutrition or PEN) might affect gut health and inflammation in people with axial spondyloarthritis (axSpA). Researchers want to see if this diet can help improve gut bacteria and reduce inflammation, similar to how it works in some bowel conditions.
United Kingdom - active not recruitingNA
Walking Football for Axial Spondyloarthritis
This study looks at whether Walking Football is a safe and helpful exercise for people with axial spondyloarthritis (axSpA), a condition causing back pain and stiffness. It aims to see if it improves health, helps people stay active, and connects them with others.
United Kingdom - recruiting
Advanced Sensor Based Functional ASsessmenTs in Axial Spondyloarthritis
This study looks at how new treatments for a type of arthritis called axial spondyloarthritis affect back movement. We're using small sensors and MRI scans to see if treatments improve stiffness and movement in the spine.
United Kingdom