- active not recruitingNA
CHAMPION-AF Clinical Trial
This study compares a small heart device (WATCHMAN FLX) with standard blood-thinning medicines (such as DOACs) for people with an irregular heartbeat called atrial fibrillation. It aims to see if the device can prevent strokes just as well as the medicines.
United States · Australia · Belgium - recruitingPHASE3
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
This study looks at how best to prevent blood clots and bleeding in people who develop an irregular heartbeat (atrial fibrillation) after bypass surgery. It compares different common blood-thinning treatments.
United States · Brazil · Canada - active not recruitingNA
Amplatzer Amulet LAAO vs. NOAC
This study compares a device that closes off a small pouch in the heart (Amplatzer Amulet) with standard blood-thinning medicines (NOACs). It aims to see which is safer and better at preventing strokes in people with an irregular heartbeat called atrial fibrillation.
United States · Australia · Canada - recruitingPHASE4
Pre- Vs. Postoperative Thromboprophylaxis in Pancreatic Surgery
This study compares when to give blood clot prevention medicine for pancreatic surgery: either before or after the operation. It aims to find the safest and most effective timing to reduce risks like blood clots and bleeding. This is important because current guidelines differ.
Canada · Finland · Norway - recruitingPHASE4
Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism
This study looks at the best way to treat small blood clots in the lungs (isolated subsegmental pulmonary embolism) in people at low risk. It compares watching carefully without treatment to giving blood-thinning medicine to reduce bleeding risks.
Belgium · Canada · France - recruitingPHASE3
Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial
This study looks at two medicines, tranexamic acid and desmopressin, to see if they can reduce serious bleeding in people with kidney disease who are having surgery. It's a first step to see if a bigger study should be done.
Canada - recruitingPHASE2, PHASE3
Bupivacaine and Epinephrine Injection Study
This study looks at a common nose operation for sinus problems. Researchers want to see if a special injection during surgery helps doctors see better and reduces bleeding, compared to having no injection at all. It's for adults aged 19 and over.
Canada - recruitingNA
Timing of Anticoagulant Administration During Radial Access Percutaneous Coronary Intervention: the HERA-PCI Study (Heparin Early for Radial Access Percutaneous Coronary Intervention)
This study looks at the best time to give blood-thinning medicine (heparin) during a heart procedure (PCI) through the wrist. We want to see if giving it earlier helps prevent a common problem where the wrist artery might get blocked.
France