- active not recruitingPHASE3
A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)
This study is testing a new medication called donanemab for people in the early stages of Alzheimer's disease. Researchers want to see if it's safe and helps improve or slow memory and thinking problems. It's a key step in understanding potential new treatments for this condition.
Argentina · Australia · China - recruitingNA
Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity
This study looks at how increasing physical activity might help slow down memory and thinking problems in people with a condition called REM sleep behaviour disorder (iRBD). This condition can sometimes lead to Parkinson's disease. Participants will use a smartphone app to boost their activity levels.
Germany - recruitingPHASE1, PHASE2
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
This study looks at new drug combinations (Elacestrant and Abemaciclib) for people with breast cancer that has spread to the brain. It aims to find the right dose and see how well the new combination works for ER-positive, HER-2 negative breast cancer.
United States · Belgium · France - recruitingNA
Treating Depression on a Day-to-day Basis: Development of a Tool for Physicians Based on a Smartphone Application
This study is checking if a smartphone app can help doctors better understand and treat depression. It aims to improve how doctors provide care by looking at daily symptoms and how well people take their medication, using a mobile phone tool to gather information.
France - recruitingNA
VIrtual Reality Glasses Use to Improve Lateropulsion and the Post-stroke Postural Vertical
This study looks at how virtual reality glasses might help people who have had a stroke and are struggling with balance and feeling aware of where straight up is. We're testing if special VR glasses can help them stand straighter and feel more stable.
France - recruiting
Biobank and Brain Health in Bordeaux.
This study, called "B cube," looks at how our brains change as we get older, especially from age 55. Researchers want to understand why some people's memories and thinking skills decline and how to prevent it. They are studying 2000 people in Bordeaux, France, focusing on things like diet and overall health.
France - not yet recruitingNA
Stroke Cerebral Reorganization Pathways (SPECTRE)
The SPECTRE study looks at how the brain recovers after a stroke, especially for arm and hand movement. Researchers use special brain scans (fMRI) and arm tests to understand why some people recover better than others, hoping to improve future stroke care.
France - active not recruitingPHASE3
A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)
This study is looking at different ways of giving a medicine called donanemab for early Alzheimer's disease. Researchers want to see how different doses affect side effects and which patients might be more likely to experience them. It's for adults aged 60-85.
United States · United Kingdom - not yet recruitingNA
Acceptability and Tolerance Market Research of a Slow Release, Phenylalanine-free Protein Substitute for the Dietary Management of Phenylketonuria
This study looks at a new type of protein supplement for children and adults with PKU. It's a slow-release tablet designed to be easier to take. Researchers want to see if people find it acceptable and if they tolerate it well, helping improve choices for managing PKU.
United Kingdom