- active not recruitingPHASE3
Olaparib Maintenance Monotherapy in Patients With BRCA Mutated Ovarian Cancer Following First Line Platinum Based Chemotherapy.
This study looks at whether Olaparib tablets can help women with advanced ovarian cancer that has a specific genetic change (BRCA mutation) after their initial chemotherapy, aiming to keep the cancer from returning for longer.
United States · Australia · Brazil - enrolling by invitation
Prophylactic Prostatectomy for Prostate Cancer (PPPC)
This study is gathering opinions about a possible operation called a prophylactic prostatectomy. This operation might reduce prostate cancer risk in men with high genetic risk. We want to understand if men would consider this surgery and what their concerns would be.
United Kingdom - active not recruiting
The IMPACT Study - Identification of Men With a Genetic Predisposition to ProstAte Cancer
The IMPACT study checks men with certain inherited gene changes (BRCA1, BRCA2, or Mismatch Repair genes) for prostate cancer. It also includes men without these changes. Researchers want to see if these gene changes increase prostate cancer risk and if screening helps.
United Kingdom - recruiting
The GENPET Study - An Imaging Study of FCH-PET-CT in Men With Prostate Cancer and a DNA Repair Gene Mutation.
This study looks at new ways to scan for prostate cancer in men with specific gene changes. We compare standard scans with a special PET-CT scan to see which is better at finding if the cancer has spread beyond the prostate.
United Kingdom