- recruitingNA
Ablation of Focal Activation in Atrial Fibrillation
This study investigates if a new mapping technique, RETRO-Mapping, can accurately find specific electrical 'drivers' of persistent atrial fibrillation (AF). We aim to see if treating these drivers, in addition to standard treatment, improves outcomes for people living with persistent AF.
United Kingdom - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A first-in-human study to learn about how safe the study drug is in healthy participants
This early-stage study is looking at a new medicine for heart rhythm problems. Researchers want to see how safe it is and how it works in healthy volunteers, before testing it in patients. It's a first step to finding new treatments.
Germany - recruitingNA
Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out of Hospital Cardiac Arrest
This study looks at using a special balloon device (REBOA) in the main artery to help people who have a sudden heart stop outside of hospital. It aims to see if this method is practical and helpful alongside standard emergency care to improve survival.
United Kingdom - recruitingNA
Cardiac Arrhythmia Telemetry; Conventional vs HeartWatch
This study compares a new device called HeartWatch with standard heart monitors (Holter monitors). It aims to see how well HeartWatch, worn on your upper arm, can detect common heart rhythm problems like atrial fibrillation and help understand your symptoms more effectively over a longer time.
Canada - recruiting
Mayo AVC Registry and Biobank
This study aims to better understand a heart condition called Arrhythmogenic Ventricular Cardiomyopathy (AVC) that can lead to sudden cardiac arrest. Researchers hope to find new genetic causes and ways to predict the disease, helping to save lives in affected families.
United States · United Kingdom - recruitingNA
Investigation of Cardioversion Versus Therapeutic Ablation for Persistent AF (ORBICA-AF)
This study compares two treatments for a type of irregular heartbeat called persistent atrial fibrillation (AF): a procedure called catheter ablation, and an electrical treatment called cardioversion. We want to see which one works better at keeping your heart rhythm normal for longer. It's for people aged 18-85.
United Kingdom - recruitingNA
The Role of Right Atrial Ectopy Triggering Ganglionated Plexuses in AF
This study looks at a new way to treat atrial fibrillation (AF), a common heart rhythm problem. It explores whether targeting specific nerve endings in the right side of the heart can help people whose AF has returned after standard treatments.
United Kingdom - recruitingNA
Smart Textile ECG Monitoring
This study looks at a special chest band, called Skiin, that can record your heart's electrical activity (ECG). It helps doctors learn more about irregular heartbeats, using comfy smart clothing and a phone app to keep an eye on your heart for two weeks.
Canada - active not recruitingNA
Virtual E-health System for Implantable Cardioverter Defibrillators
This study looks at a new way to monitor implanted heart devices remotely, like pacemakers or defibrillators. Instead of regular hospital visits, patients' devices are checked from home using a special e-health system. It compares this new remote monitoring system to the usual care.
Canada - recruitingNA
StereoTactic Ablative RadioTherapy of Cardiac Arrhythmias
This study looks at a new way to treat irregular heartbeats (arrhythmias) using a special type of radiation therapy called SBRT. It aims to see if this treatment is safe and works well for patients whose current treatments haven't helped enough.
Canada