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Arterial Revascularisation Trial - a randomised trial to compare survival following bilateral versus single internal mammary artery (IMA) grafting in coronary revascularisation
Coronary bypass surgery redirects blood around blocked heart vessels. Surgeons often use an artery from the chest wall. This UK trial compares using one chest artery against using two. Researchers want to find out if using two chest arteries helps patients live longer and reduces future heart problems over 15 years.
United Kingdom · England · Australia - recruitingNA
Virtual Ward-Assisted Very earLy dIschArge of Low-rIsk STEMI patieNTs: the VALIANT-STEMI Trial
This study looks into safely sending home some heart attack patients sooner. It compares usual hospital stays with a new approach where patients go home early and are monitored remotely by a 'virtual ward' team using telephone check-ups.
United Kingdom - recruitingPHASE1
A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
This study is testing a new medicine called CTX310 for people in the UK with high cholesterol and fats in their blood that haven't improved with usual treatments. It will check if the medicine is safe and how well people tolerate different doses. It's an early-stage study.
United States · Australia · New Zealand - recruitingNA
Strategy for EArly Recognition of Cancer, COPD & Heart Failure in the Emergency Department
This study at Queen Elizabeth University Hospital checks if a computer program can help doctors find heart and lung problems like cancer earlier from chest X-rays. It aims to improve how quickly and accurately these conditions are diagnosed.
United Kingdom - recruiting
Collection of Blood Samples for New Diagnostic Devices 2
This study helps develop new tests for conditions like blood clots, heart problems, kidney issues, and infections. It involves giving blood samples (from a vein or finger-prick) to help create quick, accurate tests that can be used at clinics, offering faster results to improve patient care.
United Kingdom - active not recruitingNA
A Single-centre Study Comparing a Non-invasive Lactate Sensor to Standard Invasive Measurements in Patients Undergoing Coronary Artery Bypass Surgery.
This study compares a new, comfortable sensor for measuring lactate levels with standard blood tests in patients having heart surgery. It aims to reduce needle pokes and help doctors quickly diagnose conditions like chest pain, improving future patient care.
United Kingdom - recruitingNA
The Role of EDHFs on Blood Pressure Following a Bout of Prolonged Sitting
This study looks at how sitting for a long time affects your blood pressure and the tiny chemicals in your arteries that help control it. We want to know if these effects last even after you've finished sitting, and if they differ between men and women.
Canada - recruitingPHASE4
Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes
This study is looking at whether giving critically ill patients blood from a donor of the same sex (male to male, female to female) improves their survival compared to getting blood from a donor of a different sex. It's a key step to see if we can make blood transfusions even safer and more effective.
Canada - active not recruitingNA
A Single Centre Study Comparing Continuous Interstitial Fluid Lactate Detection to Standard Measurements of Lactate in Patients Undergoing Elective Coronary Artery Bypass Graft Surgery and/or Valve Replacement.
This study investigates a new wearable device to continuously measure lactate levels in patients having heart surgery. It aims to see if this device can reduce the need for frequent blood tests, making recovery more comfortable and potentially speeding up emergency diagnoses.
United Kingdom