- ongoing, recruitingTherapeutic exploratory (Phase II)
Treatment of Chronic Hand Eczema with Oral Roflumilast (HERO) – a randomized controlled trial
This study called HERO is looking into a new medicine called roflumilast to see if it can help people with ongoing hand eczema. Participants will either get the new medicine or a dummy pill. We'll check if their hand eczema gets much better after 16 weeks.
Denmark - ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2, Double-Blind, Randomized, 16-Week, Vehicle-Controlled, Efficacy and Safety Study of Ruxolitinib Cream Followed by an Open-Label Extension Period in Adults With Chronic Hand Eczema
This study is testing a new cream called ruxolitinib for adults with ongoing hand eczema. It compares the new cream to a dummy cream to see how well it works and if it's safe over 16 weeks, with a longer open-label period.
Germany · Poland - ongoing, recruitingTherapeutic exploratory (Phase II)
A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety deucravacitinib in patients with chronic hand eczema
This study is testing a new unapproved medicine called deucravacitinib for people with long-lasting hand eczema. We want to see if it helps reduce the eczema and if it's safe to use, compared to a dummy pill.
Germany - recruiting
Characterization of Chronic Hand Eczema
This study looks at hand eczema and a similar skin condition called atopic dermatitis. Researchers want to understand these conditions better using gentle skin tests and scans. They will also see how these conditions affect people's daily lives over time.
Canada