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Chronic heart failure with reduced ejection fraction research hub
2 indexed studies · 0 currently recruiting
- ongoing, recruitingTherapeutic exploratory (Phase II)
(21683) Phase 2b open-label clinical study to evaluate the tolerability and safety of an initiation dose of 5 mg of Vericiguat in participants with chronic heart failure with reduced ejection fraction
This study is testing a new 5mg dose of a drug called Vericiguat for people with long-term heart failure where their heart doesn’t pump blood well. We want to see how well people tolerate this starting dose and if it's safe to use. It's an early-stage study.
Spain · Italy · Sweden - ongoing, recruitingTherapeutic confirmatory (Phase III)
A Pivotal Phase 3 Randomized, Placebo-controlled Clinical Study to Evaluate the Efficacy and Safety of the sGC Stimulator Vericiguat/MK-1242 in Adults With Chronic Heart Failure With Reduced Ejection Fraction
This study looks at a new drug, vericiguat, for people with long-term heart failure where the heart struggles to pump blood. It compares vericiguat with a dummy pill to see if it can prevent heart-related deaths or hospital stays, and if it's safe.
Sweden · Spain · Hungary