- recruitingNA
A Prospective Randomised Study of Treatment Selection Based on Epigenetic Markers Versus Standard of Care Treatment Selection in Adults With CROHN's Disease
This study looks at a new way to pick medicines for Crohn's disease. Researchers compare choosing treatments based on special genetic information (epigenetics) to the usual doctor's choice, hoping to find more effective and cost-efficient options.
Belgium · Italy · Netherlands - recruitingPHASE2
Target Engagement of EXL01 in the Prevention of Post-operative Recurrence of Crohn's Disease
This study looks at a new medicine called EXL01 to see if it can stop Crohn's disease from coming back after surgery. Patients will be given either EXL01 or a dummy pill for about six months to see if it helps.
France - recruitingPHASE1, PHASE2
Tolerance of Local Administration of Cryopreserved Autologous Stromal Vascular Fraction Combined With Micrograft for the Treatment of Refractory Ano-perineal Fistulas in Crohn's Disease
This study looks at a new treatment for severe fistulas in Crohn's disease that haven't responded to other treatments. It involves injecting a patient's own specially prepared cells to help these fistulas heal. It builds on previous research showing this treatment might be safe and effective.
France - recruitingPHASE4
De-escalation of Ustekinumab Therapy in Patients With Crohn's Disease and Ulcerative Colitis
This study looks at whether people with Crohn's disease or ulcerative colitis, who are feeling well on ustekinumab, can reduce their dose without their symptoms returning. Researchers want to see if less frequent injections still keep the disease under control.
Canada - recruitingNA
Assessing Interventions of Diet in IBD
This study looks at how different diets, like intermittent fasting, Mediterranean, and Low FODMAP, affect people with inflammatory bowel disease (IBD). We want to see which diets help symptoms, improve life quality, and are easiest to stick with.
Canada - recruiting
CEDUR - German IBD Registry
The CEDUR registry is collecting information on adults in Germany with Crohn's disease, ulcerative colitis, or indeterminate colitis. It helps doctors understand how these conditions are managed in the real world, looking at treatments, quality of life, and safety to improve care.
Germany - not yet recruitingNA
Study of Concordance Between Inflammatory Activity Assessed by Enteric MRI With and Without Intestinal Distension Product in Patients With Ileal Crohn's Disease.
This study looks at a new way to do MRI scans for Crohn’s disease. It compares scans with and without a special drink, to see if we can still get good information about inflammation without patients having to drink something that can cause uncomfortable side effects.
France - recruitingPHASE4
Efficacy of MIrikizumab to Achieve Transmural Healing in patiENTs With Crohn's Disease
This study looks at how well a medicine called mirikizumab helps people with Crohn's disease. It's for adults aged 18-75 who have active Crohn's, focusing on healing the bowel lining. The aim is to see if the treatment can make the bowel look normal inside on scans.
France - not yet recruitingPHASE2
Modafinil For Fatigue in IBD: A Feasibility Randomised Controlled Trial
This study looks at whether the drug modafinil can help reduce tiredness in people with Crohn's disease or ulcerative colitis. It compares modafinil to a dummy pill to see if it's safe and practical to run a bigger study in the future.
United Kingdom