Depressive Disorder, Major research hub
8 indexed studies · 8 currently recruiting
- not yet recruitingPHASE3
A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder
This study is looking at a new medication called Brenipatide for adults with major depression. It aims to see if this new treatment, when added to usual care, can help prevent depression symptoms from coming back compared to a dummy treatment (placebo) plus usual care.
United States · Australia · Brazil - recruitingPHASE3
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
This study is looking at a new medicine called Brenipatide for adults with major depression. It aims to see if Brenipatide, along with usual care, can help stop depression symptoms from coming back compared to usual care alone.
United States · Australia · Brazil - enrolling by invitationNA
Non-invasive Vagus Nerve Stimulation as a Tool to Modulate Stomach-Brain Coupling in Depression
This study looks at how the stomach and brain communicate in people with depression. It tests a gentle neck stimulation (tVNS) to see if it can improve this connection and help with depression symptoms. Researchers want to understand if this non-invasive treatment could be helpful.
Germany - recruitingNA
Comparing the Efficacy of fMRI-Guided vs. Standard iTBS in Treating Depression
This study looks at a new way to treat depression using brain stimulation. We're comparing standard brain stimulation with a more personalised approach, hoping to improve how well it works for people with depression.
Canada - recruitingNA
bWell-D Pilot Randomized Controlled Trial
This study tests a new virtual reality (VR) tool called bWell-D for people with depression. It aims to see if the tool helps with thinking skills and whether people find it easy and enjoyable to use.
Canada - not yet recruitingNA
Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Major Depressive Disorder (MDD)
This study is testing if a new device that uses gentle electrical pulses to stimulate a nerve near your ear can help treat depression. It compares the active device to a dummy device to see if it makes a real difference in people with major depressive disorder.
United States · United Kingdom - recruitingNA
Dopamine Modulation of Motivation and Motor Function in Major Depression & Inflammation
This study looks at how a medicine similar to L-dopa/Carbidopa might help people with depression who also have inflammation. It aims to improve motivation and movement issues often seen in depression.
Germany - recruitingNA
The Effect of Mediterranean Diet and Mindfulness Eating on Depression Severity in People With Obesity and Major Depressive Disorder
This study looks at how a Mediterranean diet and mindful eating might help people with both depression and obesity. Participants will try different approaches for 12 weeks, followed by a check-up period, to see if these changes improve their mood.
Germany