- recruitingTherapeutic exploratory (Phase II)
A randomized, double-blind, placebo-controlled, multi-center study to evaluate the efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of orally administered GLPG3667 once daily for 24 weeks in adult subjects with dermatomyositis
This study is testing a new medicine called GLPG3667 for adults with dermatomyositis. We want to see if it helps improve their condition, if it's safe to use, and how the body handles it. Participants will take either the medicine or a dummy pill for 24 weeks.
Germany · Italy · Romania - recruitingTherapeutic confirmatory (Phase III)
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of IgPro20 (Subcutaneous Immunoglobulin, Hizentra®) in Adults with Dermatomyositis (DM) – The RECLAIIM Study
This study is testing a new way to treat dermatomyositis, a condition that causes muscle weakness and skin problems. It will see how well a medicine called Hizentra works to improve symptoms and if it's safe, compared to a dummy treatment. We hope to find a better treatment for people with this condition.
Hungary · France · Italy - recruitingPHASE2, PHASE3
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
This study looks at a new treatment called CABA-201 for conditions that cause muscle weakness and inflammation, like dermatomyositis. It aims to see how safe and effective this treatment is for adults and children whose condition hasn't improved with usual care.
United States · Germany · Italy - active not recruitingPHASE3
A Study to Investigate the Efficacy and Safety of Brepocitinib in Adults With Dermatomyositis
This study is looking into a new medication called brepocitinib for adults with dermatomyositis. Researchers want to see if it's safe and helps improve symptoms compared to a placebo. Participants will receive either the new drug or a dummy pill for a year.
United States · Argentina · Belgium - recruitingPHASE2
Subcutaneous Injection of Sodium Thiosulfate for Ectopic Calcifications or Ossifications. A Pilot Study
This study looks into a new way to treat hard lumps under the skin caused by certain illnesses like Systemic Sclerosis and Dermatomyositis. Researchers are testing a medicine called Sodium Thiosulfate (STS), given as an injection, to see if it can help reduce these lumps and improve patients' lives.
France - recruitingPHASE3
Baricitinib in Patients With Relapsing or naïve Dermatomyositis
This study is testing a new medicine called baricitinib for dermatomyositis, a rare muscle and skin condition. It aims to see if baricitinib, alongside usual care, can help lessen symptoms and reduce the need for strong steroids in adult patients.
France - active not recruitingPHASE2, PHASE3
A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.
This study looks at a new drug, efgartigimod PH20 SC, for adults with active idiopathic inflammatory myopathy (IIM), a condition causing muscle weakness and inflammation. It compares the drug to a dummy treatment to see if it helps improve muscle strength and overall well-being.
United States · Argentina · Australia - enrolling by invitationPHASE3
A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy
This study looks at a new medicine called efgartigimod for people with certain muscle conditions like myositis. It's for adults who were in a previous study, to see if the medicine is safe and helpful over a long time.
United States · Argentina · Austria